茵陈盆草汤治疗新生儿母乳性黄疸疗效观察

Treatment of newborn breast-milk jaundice using artemisia capillaris trough grass soup

[目的]探讨以口服中药茵陈盆草汤治疗新生儿母乳性黄疸疗效。[方法]对102例新生儿母乳性黄疸患儿随机分为三组,治疗组34人采用中药汤剂口服治疗,对照组34人口服鲁米那治疗,纯母乳喂养组34人未经治疗;观察治疗前后胆红素、体重、大便次数和血红蛋白的变化。[结果]治疗前各项各组间无显著差异,中药汤剂治疗后胆红素的测定结果为(101±24.7)μmol/L,明显低于鲁米那治疗组和纯母乳喂养组(183±31.5)和(205±33.2)μmol/L,具统计学意义,P<0.01;并且,中药汤剂治疗后血红蛋白的变化为(173±8.2)g/dL,明显高于鲁米那治疗组和纯母乳喂养组(166±9.8)和(168±7.7)g/dL,具统计学意义,P<0.01;中药汤剂治疗后体重、大便次数的变化与鲁米那治疗组和纯母乳喂养组差异无显著意义,P>0.05。[结论]茵陈盆草汤治疗新生儿母乳性黄疸值得推广。

[ Objective ] To explore the effects of artemisia capillaris trough grass soup in the treatment of newborn breast - milk jaundice;[ Methods] one hundred and two infants with breast milk jaundice were randomly grouped into three treatment sub -groups： artemisia capillaris trough grass soup therapy group （n = 34）, luminal group （n = 34） for comparison of treatment efficacies of such methods and their effect on breast feeding, bilirubin, body weight, times of stool and Hemoglobin Level were observed before and after treatment. [ Results] No difference was found in bilirubin, body weight, times of stool and Hemoglobin Level in the three groups before treatment. After treatment , The level of bilirubin in herbal medicine group was （101 ±24.7） μmol/L lower than that in luminal group and breast feeding group （183 ± 31.5 ）and （205 ± 33.2）μmol/L （P 〈 0.01 ） ; And the Level of Hemoglobin in herbal medicine group after is（ 173 ± 8.2）g/dL, much higher than that in luminal group and breast feeding group （166 ±9.8）and（ 168 ±7.7）g/dL, P 〈0.01. There is no obvious difference on body weight or times of stool among these three groups, P 〉 0.05. [ Conclusions ] The artemisia capillaris trough grass soup is safe and effective in treating newborn breast - milk jaundice.