膀胱类癌的诊治体会(附3例报告)

The Diagnosis and Treatment of Carcinoid Tumor of Urinary Bladder (Report of 3 Cases)

目的探讨膀胱类癌的临床诊断及治疗方法。方法回顾性分析3例膀胱类癌患者的临床和病理资料,3例均为男性,年龄33～49岁。临床症状主要为无痛性肉眼血尿,无面色潮红、心悸、腹泻等类癌综合征表现。均经膀胱镜下活检病理证实。3例患者均行手术治疗。结果1例患者术后6月复发,再次手术后3月复发,最终死于肿瘤转移;1例术后随访1年复发,再次手术6月后原位复发,最终行膀胱全切术,术后随访至今未见复发和转移;1例随访3年均未见复发和转移。结论膀胱类癌发病率较低,确诊需靠组织病理学及免疫组织化学检查。其侵袭性强,预后差,播散和转移较快,治疗以手术切除为主,手术中注意切口及周围组织的保护。

Objective To study the diagnosis and treatment of carcinoid tumors of the urinary bladder. Methods The clinical and histopathologic data of 3 carcinoid tumor of the urinary bladder were retrospectively analysed.All patients were presented with gross hematuria, but with no clinical manifestations of the carcinoid syndrome such as flush, tachycardia, diarrhea. Results 3 patients received partial cystectomy. One patients was reoperated after 6 months for tumor recurred, and died of the tumor metastasis after 3 months; one patients was reoperated at 12 months and 18 months for tumor recurred after first operation, at last undergoing radical cystectomy. One patients were still alive 3 years following the surgical treatment. Conclusion Carcinoid of the urinary bladder is uncommon, the diagnosis depends on histopathological and immunohistochemical tests. Surgical intervention is the mainstay to treat it.