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序贯疗法治疗中风病偏瘫及对患者血浆ET-1、NO的影响 被引量:10

Sequential acupuncture method for treatment of apoplexy hemiplegia and its effects on plasma ET-1 and NO levels
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摘要 目的:观察序贯疗法治疗中风病偏瘫的临床疗效,并探讨其作用机理。方法:将144例中风病偏瘫患者随机分为序贯疗法组(治疗组)和传统针刺组(对照组)各72例。治疗组根据患者处于软瘫期、痉挛期、相对恢复期、后遗症期选取不同的穴位,对照组统一采用常规取穴。治疗3个月后观察临床疗效,检测患者血浆内皮素(ET-1)、一氧化氮(NO)水平。结果:治疗组在改善患者神经功能缺损程度、总的生活能力状态、临床综合疗效、促进康复进程及降低血浆ET-1、升高NO水平等方面优于对照组(P<0.05,P<0.01),且病程越短,疗效越佳。结论:序贯疗法治疗中风病偏瘫疗效显著,能降低血浆ET-1、升高NO水平,为治疗中风病偏瘫的有效疗法。 Objective To observe clinical therapeutic effect of sequential acupuncture method on apoplexy hemiplegia and to probe into the mechanism. Methods One hundred and forty-four cases of apoplexy hemiplegia were randomly divided into a treatment group treated with sequential acupuncture method and a control group treated with traditional acupuncture, 72 cases in each group. After treatment for 3 months, their clinical therapeutic effects were observed and plasma endothelin-1 (ET-1) and nitric oxide (NO) levels were detected. Results The treatment group in the improvement of the nerve function-deficiency, total life ability and clinical overall effect, and the course of recovery, decreasing of ET-1 level and increasing of NO level was superior to the control group (P〈0. 05, P〈0. 01), the shorter the course, the better the therapeutic effect. Conclusion The sequential acupuncture method has an obvious therapeutic effect on apoplexy hemiplegia, and it can decrease plasma ET-1 level and increase NO level. It is an effective therapy for apoplexy hemiplegia.
出处 《中国针灸》 CAS CSCD 北大核心 2007年第4期237-240,共4页 Chinese Acupuncture & Moxibustion
基金 湖南省教育厅科研项目:04C433
关键词 中风/针灸疗法 偏瘫/针灸疗法 针刺疗法/方法 内皮素1/血液 一氧化氮/血液 Stroke/am ther Hemiplegia/am ther Acupuncture Therapy/methods Endothelin-1/blood Nitric Oxide/blood
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