1Scherer PE,Williams S,Fogliano M,et al.A novel serum protein similar to C1q,produced exclusively in adipocytes[J].J Biol Chem,1995,270(45):26746-26749
2Schaffler A,Barth N,Palitzsch KD,et al.Mutation analysis of the human adipocytespecific apM21 gene[J].Eur J Clin Invest,2000,30(10):879-887
4Yamauchi T,Kamon J.Cloning adiponectin receptors that mediate antidiabetic metabolic effets[J].Nature,2003,423:762-769
5Utpal BP,Xueliang D,Terry PC,et al.Structurfunction studies of the adipocytesecrered hormone Acrp30 Padiponectin[J].Biol Chem,2003,278(11):9073-9085
6Hironori W,Toshimasa Y.Impaired multimerization of human adiponectin mutants associated with diabetes[J].Biol Chem,2003,278(41):40352-40363
7Trimarco B,Volpe M,Ricciardelli B,et al.Studies of the mechanisms underlying impairment of beta-adrenoceptor-mediated effects in human hypertension[J].Hypertension,1983,5:584 -590
8Y.Hattori,M.Suzuki,S.Hattori,et al.Globular adiponectin upregulates nitric oxide production in vascular endothelial cells[J].Diabetologia,2003,46:1543-1549
9Matsubara M,Katayose S,Maruoka S.Decreased plasma adiponectin concentrations in nondiabetic woman with elevated homeostasis modelassessment ratios[J].Eur J Endocrinol,2003,148(3):343-350
10Stefan N,Stumvoll M.Adiponectinits role in metabolism and beyond[J].Horm Metab Res,2002,34 (9):469-474
二级参考文献66
1Ouchi N, Kihara S, Arita Y, et al. Adipocyte-derived plasma protein,adiponectin, suppresses lipid accumulation and class A scavenger receptor expression in human monocyte-derived macrophages. Circulation,2001,103:1057-1063.
2Yu S, Matsusue K, Kashireddy P, et al. Adipoeyte-specific gene expression and adipogenic steatosis in the mouse liver due to peroxisome proliferator-activated receptor gamma1 (PPARgamma1) overexpression.J Biol Chem, 2003,278: 498-505.
3Yamamoto Y, Hirose H, Saito I, et al. Correlation of the adipocyte-derived protein adiponectin with insulin resistance index and serum highdensity lipoprotein-cholesterol, independent of body mass index, in the Japanese population. Clin Sci( Lond), 2002,1
4Hotta K, Funahashi T, Bodkin NL, et al. Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys. Diabetes, 2001,50:1126-1133.
5Arita Y, Kihara S, Ouchi N, et al. Paradoxical decrease of an adipocyte specific protein, adiponectin, in obesity. Biochem Biophys Res Commun, 1999,257: 79-83.
6Yamauchi T, Kamon J, Minokoshi Y, et al. Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP activated protein kinase. Nat Med,2002,8: 1288-1295.
7Combs TP, Wagner JA, Berger J, et al. Induction of adipocyte complement-related protein of 30 kilodaltons by PPARgamma agonists:a potential mechanism of insulin sensitization. Endocrinology, 2002, 143: 998-1007.
8Stumvoll M, Haring H. The peroxisome proliferator-activated receptorgamma2 Prol2Ala polymorphism. Diabetes,2002,51:2341-2347.
9Yamamoto Y, Hirose H, Miyashita K, et al. PPAR(gamma)2 gene Pro12Ala polymorphism may influence serum level of an adipocyte-derived protein, adiponectin, in the Japanese population. Metabolism,2002,51:1407-1409.
10Thamer C, Machicao F, Fritsche A, et al. No influence of the PPARgamma2 Pro12Ala genotype on serum adiponectin concentrations in healthy Europeans. Metabolism, 2003,52: 798-799.
