雪乐通与弥可保联合治疗糖尿病周围神经病变的临床疗效观察

Therapeutic effect of Xueletong combined methycobal on diabetic peripheral neuropathy

目的观察雪乐通与弥可保联合治疗糖尿病周围神经病变的临床疗效。方法选择60例糖尿病合并周围神经病变患者,将其随机分成两组,治疗组30例,用雪乐通20ml加生理盐水500ml静滴,1次/d,同时应用弥可保500μg,肌肉注射,1次/d,连续2周。对照组30例用弥可保500μg,肌肉注射,1次/d,连续2周。结果治疗2周后两组神经症状与检查评分均明显下降,但以治疗组下降显著,治疗后两组平均评分差异有统计学意义(P<0.01)。结论雪乐通与弥可保联合治疗糖尿病周围神经病变有较好疗效。

Objective To observe the clinical efficacy of Xueletong and methycobal on diabetic peripheral neuropathy. Methods Two groups of patients who had diabetic peripheral neuropathy with comparative conditions were randomly divided into a therapeutic group（ 30 cases） and a control group（ 30 cases）. The patients of the therapeutic group were given Xueletong 20ml dissolved in 0.9% sodium chloride 500mL once a day intravenously, and given methycobal 500μg once a day intramuscularly,and in the control group were only given methycobal 500 μg once a day intramuscularly. Two groups of patients all had one course of treatment for 2 weeks. Rusults After 2 weeks＇treatment, evaluating score of neural symptoms of two groups decreased in both groups, but more distinctly in the therapeutic group （ P 〈 0.01 ）. Conclusion The therapeutic effects of Xueletong combined methycobal on diabetic peripheral neuropathy is obvious.