右股动脉粥样硬化性狭窄与冠心病关系的观察

Relation of right femoral atherosclerosis stenosis to coronary artery disease

目的:评价右股动脉粥样硬化性狭窄(RFASS)与冠状动脉粥样硬化(CAAS)的关系。方法:41例行冠状动脉造影患者根据结果分为正常组和冠心病组。冠心病组根据冠状动脉病变支数分为一支病变组和二支病变组、三支病变组。冠状动脉造影同时行右股动脉造影,观察右股动脉有无狭窄及狭窄程度,计算狭窄评分。结果:冠心病组RFASS发生率与正常组无显著性差异;随冠状动脉病变支数的明显增加,RFASS评分增大;RFASS预测冠心病的敏感性、特异性分别为58.1%、80%。结论:冠状动脉病变者RFASS的发生率高,在一定程度上,冠状动脉程度越重RFASS的程度亦越重,二者间存在正相关。RFASS对预测冠状动脉病变的敏感性欠佳,尚不支持其作为冠心病的筛查指标。RFASS及(或)双侧股动脉粥样硬化性狭窄可否作为冠心病的独立危险因素,有待大样本的研究进一步验证。

Objective：To investigate the relation of right femoral atherosclerosis stenosis （RFASS）to coronary artery disease （CAD）. Methods：Right femoral angiography was conducted among 41 patients when they received coronary angiography （CAG）. These patients were divided into normal group and CAD group by the results of CAG. CAD group was divided into single-vessle group（ n = 15 ） ,double- vessle group（ n = 8）and three-vessle group（ n = 8）. The existence and the extent of RFASS was observed and recorded. RFASS scores were calculated. Results ：The incidence of RFASS in CAD group was not significantly higher than that in normal group. With the number of coronary vessles of atherosclerosis increasing, the scores of RFASS significantly increased. The predictive sensitivity and specifity of RFASS for CAD were 58.1% and 80% respectively. Conclusion：The positive rate of RFASS in CAD was high. To some extent, the more severe CAAS was, the more RFASS was, there was positive correlation between them. The predictive sensitivity of RFASS for CAD was not so high that it could not regarded as good screening marker in CAD yet. Whether RFASS or FASS was an independent risk factor for CAD, more trials with a large number of samples were needed.