异丙酚用于心血管病人口腔颌面部手术麻醉诱导和鼻插管时的观察

Observation on effects of Propofol during anesthetic induction and nasotracheal intubation for oral maxillofa- cial surgical patients with cardiovascular diseases

选用新型静脉麻醉药异丙酚(Propofol)用于心血管病人口腔颌面麻醉诱导鼻腔插管13例,并与硫贲妥钠等对比,结果表明:插管前两组血液动力学指标,包括平均动脉压(MAP)、心率(HR)无显著性差异(P>0.05),插管后1,3,5分钟不同时段,异丙酚组血液动力学波动明显低于硫贲妥钠组,二者有显著性差异(P<0.01)。提示异丙酚用于心血管病人鼻腔插管优于硫贲妥钠等药物。

In 13 patients with cardiovascular diseases. ASA grade Ⅱ to Ⅲ , undergoing oral maxillofacial surgery, the effect of new intravenous anesthetic Propofol was studied during anesthetic induction and nasotracheal intubation, and compared with control group (Sodium Thiopental). The results showed hemodynamics such as mean arterial pressure(MAP), heart rate (HR) hadn't any significant differences between two groups before nasotracheal intubation (P>0. 05). But the hemodynamincs had significant differences between two groups at 1,3 and 5 mins after nasotracheal intubation ( P <0. 01). Arrhythmias in Propofol group are less significant than in contrast group. It is concluded that it is better to use Propofol than Thiopental in patients with cardiovascular diseases for oral maxillofical surgery in the period of anesthetic induction and nasotracheal intubation.