椎-基底动脉与脑干位置关系的MRI研究

MRI Research of the Relationship between Brain Stem and Vertebral-basilar Artery

目的研究颅内椎基底动脉与脑干的空间关系及其与脑内MRI表现及临床症状的相关性。方法具有脑部症状或体征、临床综合检查排除相关疾病患者85例,无头部症状的正常志愿者85例。回顾性研究头部轴面MRI图像,记录研究组与对照组颅内椎基底动脉与脑干关系的分级及脑内MRI表现分型,对观察资料与临床资料进行统计分析。结果研究组血管压迫脑干发生率51%,对照组14%,两者差异具有统计学意义(χ2=7.106,P<0.01)。血管压迫脑干的程度与患者年龄、颅内缺血性MRI表现及患者症状均具有相关性。年龄越大、椎基底动脉供血区有缺血性MRI表现及患者具有其他原因难以解释的脑干症状者出现血管压迫脑干的概率越高。结论颅内段椎基底动脉压迫脑干与某些脑部症状的形成有关,发生压迫的部分原因为动脉硬化。

Objective：To investigate the relationship between the oppression of brain stem by the vertebral-basilar artery and their MRI signs of brain and clinical symptoms. Methods： MRI of head was performed in 85 patients as the test group who had brain symptoms on MRI and 85 healthy volunteers as the control group in this retrospective study. The features and the relationship between the oppression of the brain stem by the vertebral-basilar artery on MRI were investigated in single blind procedure in all patients. The results were analyzed statistically. Results：The oppression of brain stem by the vertebral-basilar artery was found in 51 per cent of cases in the test group and 14 per cent in the control group respectively. There was significant difference between the two groups （χ^2=7.106,P〈0.01 ）. Through logistic regressive analysis, the frequency and degree of oppression of the brain stem was proportional to the age,ischemic signs on MRI and the symptoms in the test group. The older the age, the more ischemic signs on zones provided by vertebral artery on MRI and the more brain stem symptoms with reasons unknown, the higher the frequency of oppression of brain stems. Conclusion： Brain stem oppression caused by vertebral-basilar artery is the reason of some brain symptoms. The cause of the oppression is concerned with arteriosclerosis partially.