左卡尼汀腹膜透析患者的临床疗效分析

Clinical analysis of therapeutic effect of levocarnitine on dialysis patients.

目的观察左卡尼汀对腹膜透析患者的治疗作用。方法选择40例腹膜透析患者,随机分成对照及治疗组,各20例。治疗组每次口服1.0g左卡尼汀治疗,2次/1d,时间3个月,对照组用生理盐水。结果治疗组患者体力、食欲、恶心、睡眠倒置、心力衰竭症状改善十分显著(P<0.01),血浆总蛋白、白蛋白明显上升(P<0.01)。而对照组以上各项均无变化。结论左卡尼汀能明显改善腹膜透析患者临床症状,减少心力衰竭发生。

Objective To observe the therapeutic effect of L- camitine on peritoneal dialysis patients. Methods Forty peritoneal dialysis patients were randomly divided into treatment group （20 cases） and control group （20 cases）, 1.0g of L - camitine was given to the patients in treatment group twice a day for 3 months, while normal saline was given to the control group, Results In the treatment group, physical, nausea, vomiting, inversion of sleep, heart failure were improved significantly （P〈 0.01）, and serum albumin was also elevated in the treatment group （ P 〈 0.01 ）, Conclusion L- carnitin is effective for improving of clinical symptoms of patients under peritoneal dialysis and reducing the occurrence of heart failure.