龙岗区育龄人群地中海贫血筛查干预效果分析

Screening of thalassemia and intervention in women of child-bearing age in Longgang District of Shenzhen City.

目的了解龙岗地区育龄人群地中海贫血的发生情况。方法利用具备优生咨询及群体筛查等技术实力的计划生育服务网络,进行龙岗区10个镇(街道)的育龄人群地中海贫血筛查干预,对高风险夫妇建议做产前诊断。结果干预后育龄人群对相关地贫知识答对率比干预前有显著性提高,经筛查育龄人群地贫发生率为9.80%,再经基因诊断确诊,α地贫和β地贫的发生率分别为6.60%和3.10%。结论利用计生服务网络进行育龄人群的筛查干预,是目前减少地中海贫血(尤其是重症的)患儿出生的既经济又有效的措施。

Objective To understand the incidence of thalassemia in women of childbearing age in the locality. Methods The screen and intervention of talassemia in women of child - beating age in Longgang District were carried out by means of family planning service network aiming at eugenics consultation and mass screening, Prenatal diagnosis was advised to couples at high risk. Results The relevant knowledge of thalassemia in women of child - bearing age after intervention was significantly enhanced, The incidence of β - thalassemia in population of child - bearing age was 9.80%. The incidence rates of α - thalassemia and β - tha- lassemia as genetically diagnosed were 6.60% and 3.10%. Conclusion To screen and intervene talassemia in women of child - beating age is an economic and effective measures for reducing the birth rate of children with thalassemia by utilization of family planning network.