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幽门螺杆菌毒力因子Cag A与动脉粥样硬化

Cytotoxin associated protein A of Hp and atherosclerosis
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摘要 幽门螺杆菌的毒力因子Cag A在动脉粥样硬化发病机制中起重要作用,Cag A阳性的Hp感染能增加动脉粥样硬化的危险度,并通过抗原模拟、诱导自身免疫反应以及增强全身或动脉局部的炎症反应等途径促进动脉粥样硬化的发生发展。 Cytotoxin associated protein A of Hp plays an important role in the pathology of atherosclerosis. Cag A＋ Hp infection could be an independent risk of atherosclerosis. Molecule mimicry, autoimmune reaction and increased inflammation may be the mechanisms in accelerating atherosclerosis.
作者 陈星海 王育珊 王江滨
机构地区 吉林大学第二医院急救医学科
出处 《国际消化病杂志》 CAS 2007年第2期81-83,共3页 International Journal of Digestive Diseases
基金 国家自然科学基金(项目编号30471619) 吉林省科委基金(项目编号20050408-2)资助课题
关键词 幽门螺杆菌 细胞毒素相关蛋白 动脉粥样硬化 Hp Cytotoxin associated protein A（Cag A） Atherosclerosis
分类号 R543.5 [医药卫生—心血管疾病]
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参考文献18

  • 1Singh RK,McMahon AD,Patel H,et al.Prospective analysis of the association of infection with CagA bearing strains of Helicobacter pylori and coronary heart disease.Heart,2002,88:43-46
  • 2Gunn M,Stephens JC,Thompson JR,et al.Significant association of cagA positive Helicobacter pylori strains with risk of premature myocardial infarction.Heart,2000,84:267-271
  • 3Figura N,Palazzuoli A,Faglia S,et al.Infection by CagA-positive Helicobacter pylori strains in patients with ischemic heart disease:prevalence and association with exercise-induced electrocardiographic abnormalities.Dig Dis Sci,2002,47:831-836
  • 4Shmuely H,Passaro DJ,Vaturi M,et al.Association of CagA + Helicobacter pylori infection with aortic atheroma.Atherosclerosis,2005,179:127-132
  • 5Gabrielli M,Santoliquido A,Cremonini F,et al.CagA-positive cytotoxic Hp strains as a link between plaque instability and atherosclerotic stroke.Eur Hear J,2004,25:64-68
  • 6Pellicano R,Parravicini PP,Bigi R,et al.Infection by Helicobacter pylori and acute myocardial infarction.Do cytotoxic strains make a difference? New Microbiol,2002,25:315-321
  • 7Mayr M,Kiechl S,Mendall MA,et al.Increased Risk of Atherosclerosis Is Confined to CagA-Positive Helicobacter pylori Strains.Prospective Results From the Bruneck Study.Stroke,2003,34:610-615
  • 8Preusch MR,Grau AJ,Buggle F,et al.Association between cerebral ischemia and cytotoxin-associated gene-A-bearing strains of Helicobacter pylori.Stroke,2004,35:1800-1804
  • 9Pietroiusti A,Diomedi M,Silvestrini M,et al.Cytotoxin-Associated Gene-A-Positive Helicobacter pylori Strains Are Associated With Atheroselerotic Stroke.Circulation,2002,106:580-584
  • 10Diomedi M,Pietroiusti A,Silvestrini M,et al.Cag A-positive Helicobacter pylori strains may influence the natural history of atherosclerotie stroke.Neurology,2004,63:800-804
国际消化病杂志
2007年 第2期

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