摘要
人类基因组计划(HGP)的完成,宣告了后基因组时代的到来,其中蛋白质组学已成为研究的重点。随着蛋白质组学研究的不断深入,现已形成一个“肿瘤蛋白质组学”的分支。肿瘤蛋白质组学可动态、整体、定量地观察肿瘤发生、进展中蛋白质种类、数量的改变,现已广泛用于各种肿瘤的研究。结直肠癌是人类的一种常见的恶性疾病,肿瘤蛋白质组学在寻找结直肠癌的肿瘤生物标记物,研究结直肠癌发生的分子机制和挖掘药物的抗癌靶点等方面得到了很好的应用。
After the achievement of human genome project (HGP), the post-genome era is coming. The proteomics has become a hot. We have made a lot of research on cancer proteomics which is the new embranchment of proteomics. Cancer proteomics can observe the changes of kinds and quantity of protein which appear during the advance of carcinoma. Colorectal cancer is a very common disease. Cancer proteomics can be used to find the carcinoma biomarkers, the molecular mechanism and the anticancer drug targets.
出处
《国际消化病杂志》
CAS
2007年第2期94-96,共3页
International Journal of Digestive Diseases
关键词
蛋白质组学
结直肠癌
研究进展
Proteomics
Colorectal cancer
Research advances