摘要
子痫前期的发病原因不明,关于血栓形成倾向在子痫前期的发病机制中所起的作用是有争议的。子痫前期患者胎盘局部存在着比正常妊娠广泛的多的微血栓,这表明与血栓形成倾向有关的胎盘微血栓形成和胎盘功能不全与重度子痫前期的发病有一定的因果关系。该文主要对不同类型的子痫前期与血栓形成倾向、抗凝治疗和妊娠结局的研究进展加以综述。
The etiology of preeclampsia remains unknown. The role of thrombophilia in pathogenesis of preeclampsia is controversial. Extensive and severe placental microinfarcts and microthrombosis were observed in those women with preeclampsia, suggesting a cause-andeffect relationship between placental microthrombosis associated with thrombophilias, placental dysfunction and severe preeclampsia. The article reviewed progress in research on relationship between thrombophiha and varied types of preeclampsia, anticoagulant therapy and pregnancy outcomes and so on.
出处
《中国妇幼健康研究》
2007年第2期131-134,共4页
Chinese Journal of Woman and Child Health Research
关键词
子痫前期
血栓形成倾向
围产结局
抗凝治疗
preeclampsia
thrombophilia
pregnancy outcome
anticoagulant therapy
