期刊文献+

女性泌尿生殖道解脲支原体基因分型的研究 被引量:2

A study on genotyping of ureaplasma urealyticum in female genitourinary tract
下载PDF
导出
摘要 解脲支原体主要存在于人类泌尿生殖道及生殖腺中,是引起泌尿生殖系统感染及男女不孕不育的主要病原体,也是性传播的常见病原体,对这种条件致病病原体进一步分群分型是判断感染与携带状态的关键,故解脲支原体的基因分型是目前研究的热点。该文对解脲支原体在女性泌尿生殖道的致病机理、基因分型和分型的方法及其基因分型与临床流行病学之间关系的研究进展进行综述,探讨解脲支原体的基因分型在女性泌尿生殖道感染发病机制研究中的重要作用。 Ureaplasma urealyticum(UU) parasitizes mainly in genitourinary tract and genital gland of mankind. It is a major pathogen that causes not only infection of genitourinary system but also infertility of the males or the females, and also, it is a common pathogen of sexually transmitted disease (STD). Further genotyping for this opportunistic pathogen is the key to judge infection and pathogen carrying state, so genotyping of ureaplasma urealyticum becomes a hot spot of the study at present. In this paper, we summarized progress in research on pathogenesis, genotyping, genotyping method of ureaplasma urealyticum and relationship of genotyping of ureaplasma urealyticum with clinical epidemiology of the disease so as to explore important roles of genotyping of UU in research on pathogenesis of female genitourinary tract infection .
出处 《中国妇幼健康研究》 2007年第2期155-158,共4页 Chinese Journal of Woman and Child Health Research
关键词 解脲支原体 基因分型 泌尿生殖系统感染 携带状态 流行病学 ureaplasma urealyticum genotyping infection of genitourinary tract carrying state epidemiology
  • 相关文献

参考文献17

  • 1Kong F.Integrated genetic study of two conditional human perinatal pathogens-ureaplasmas and group B streptococci[J].Abstracts Infection Genetics and Evolution,2003,2:235-321.
  • 2Hashimoto O,Yoshida T,Ishiko H,et al.Quantitative detection and phylogeny-based identification of mycoplasmas and ureaplasmas from human immunodeficiency virus type 1-positive patients[J].J Infect Chemother,2006,12 (1):25-30.
  • 3Lukic A,Canzio C,Patella A,et al.Determination of cervicovaginal microorganisms in women with abnormal cervical cytology:The role of Ureaplasma urealyticum[J].Anticancer Res,2006,26 (6):4843-4849.
  • 4Yi J,Yoon B H,Kim E C.Detection and biovar discrimination of Ureaplasma urealyticum by real-time PCR[J].Mol Cell Probes,2005,19 (4):255-260.
  • 5Aaltone R,Jalava J,Laurikainen E,et al.Cervical ureaplasma urealyticum colonization:Comparison of PCR and association with preterm birth[J].Scand J Infect Dis,2002,34 (1):35 -40.
  • 6Cultrera R,Seraceni S,Germani R,et al.Molecular evidence of Ureaplasma urealyticum and Ureaplasma parvum colonization in preterm infants during respiratory distress syndrome[J].BMC Infect Dis,2006,6:166.
  • 7Smorgick N,Frenkel E,Zaidenstein R,et al.Antibiotic treatment of intra-amniotic infection with ureaplasma urealyticum:A case report and literature review[J].Fetal Diagn Ther,2007,22 (2):90-93.
  • 8Fernandez M C,latino M A,Zamora M Y,et al.Development of a multiple PCR method for the identification of Ureaplesma urealyticum[J].Rev Argent Microbiol,2003,35 (3):138-142.
  • 9Pkhaladze N D,Mamamtavrishvili I D,Kalandadze I V,et al.Vaginosis in patients with antenatal foetus death[J].Georgian Med News,2006,138:73-77.
  • 10Butrimiene I,Ranceva J,Griskevicius A.Mycoplasmal infection inpatients with reactive arthritis and seronegative spondy loarthrpaties[J].Medicina(Kaunas),2003,39(5):460-463.

同被引文献21

  • 1VANCUTSEM E, ECHAHIDI F, VAN GEEL K, et al. Production of recombinant antigens of ureaplasma parvum serotypes 3 and 6 for development of a serological assay [ J ]. Clin Vaccine Immunol, 2008, 15(3) :447-451.
  • 2SAUNIER M, MONNIER-BENOIT S, MAUNY F,et al. Analysis of human papillomavirus type 16 ( HPV16 ) DNA load and physical state for identification of HPV16-infected women with high- grade lesions or cervical carcinoma [ J ]. J Clin Microbiol,2008,46( 11 ) :3678-3585.
  • 3BARON C, HENRY M, TAMALET C, et al. Relationship between HPV 16, 18, 31, 33, 45 DNA detection and quantitation and E6/E7 mRNA detection among a series of cervical specimens with various degrees of histological lesions [ J ]. J Med Virol, 2015,87(8): 1389-1396.
  • 4LIU L, CAO G, ZHAO Z, et al. High bacterial loads of ureaplasma may be associated with non-specific cervicitis [ J ]. Scand J Infect Dis, 2014, 46 ( 9 ) : 637-641.
  • 5XIAO L, GLASS JI, PARALANOV V, et al. Detection and characterization of human ureaplasma species and serovars by real-time PCR [ J ]. J Clin Microbiol, 201 O, 48 ( 8 ) : 2715 -2723.
  • 6TRIANTAFILOU M, DE GLANVILLE B, ABOKLAISH AF,et al. Synergic activation of toll-like receptor (TLR) 2/6 and 9 in response to ureapiasma parvum & urealyticum in human amniotic epithelial cells [J]. PLoS One,2013, 8(4) :e61199.
  • 7XIAO L, CRABB DM, DAI Y,et al. Suppression of antimicrobial peptide expression by ureaplasma species [J]. Infect Immun,2014,82(4) :1657-1665.
  • 8CHAIM W, HOROWITZ S, DAVID JB, et al. Ureaplasma urealytieum in the development of postpartum endometritis [ J ]. Eur J Obstet Gynecol Reprod Bio1,2003,109 (2) : 145-148.
  • 9REYES L, REINHARD M, BROWM MB. Different inflammatory responses are associated with ureaplasma parvum-induced UTI and urolith formation [ J ]. BMC Infect Dis,2009, 9:9.
  • 10Frφlund M, Bjomelius E, Lidbrink P, et al. Comparison between culture and a multiplex quantitative real - time polymerase chain re- action assay detecting ureaplasma urealyticum and U. parvum [ J ]. PLoS One, 2014, 9(7) : e102743.

引证文献2

二级引证文献6

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部