禽网状内皮组织增生病病毒分子生物学特性与免疫抑制

The Immunosuppression and Molecular Biological Characteristics of Avian reticuloendotheliosis virus

禽网状内皮组织增生病病毒为反转录病毒科禽类C型反转录病毒。禽网状内皮组织增生病病毒感染后主要引起感染家禽免疫功能抑制和慢性肿瘤,该病的控制对养禽业的健康发展和生物制品质量的提高具有重大影响。文章对禽网状内皮组织增生病病毒的生物学特性与引起免疫抑制机制的研究新进展进行了简要综述。

Reticuloendotheliosis virus is a kind of bird species C type retrovirus, which belongs to retroviridae. And it is the next category correlated with mouse type C oncovirus. REV is one of the most important infectious pathogens in poultry industry. REV can cause immune suppression and chronic tumour development in chicken. Controlling this virus will bring great effect on healthy development of poultry industry and elevation of avian biologic product. The paper reviewed research progress on the mechanism of immunosuppression and molecular biological characteristics of avian REV.