胸腹水标本分离菌构成与耐药性

Constitution and their drug resistance of clinical isolated bacteria in hydrothorax-peritoneum samples

目的探讨胸腹水标本分离菌构成及其耐药性。方法对2004年1月至2005年12月临床送检胸腹水标本细菌培养和药敏试验资料进行回顾性分析。结果(1)1 682例胸腹水标本细菌培养阳性276例,阳性16.4%,检出病原菌327株,以铜绿假单胞菌、金黄色葡萄球菌、表皮葡萄球菌、大肠埃希菌最多见。(2)胸水标本G+球菌与G-杆菌构成比接近,腹水标本G-杆菌占优势(63.5%)。(3)4种主要病原菌对链霉素、庆大霉素、氨苄西林、羧苄西林、克林霉素耐药,亚胺培南、舒普深、美洛西林则显示敏感,其他抗菌药物呈现不同程度的耐药。结论加强腹水标本的细菌学检查,依据药敏试验合理使用抗菌药物,对胸腔感染的诊断与治疗具有重要价值。

Objective To investigate the bacteriological feature and drug-fast of bacteria in hydrothorax-peritoneum. Method The retrospective analysis of bacteria culture and drug-sensitive test in hydrothorax-peritoneum preparation collected from 2004. 1 to 2005.12 was done. Results （ 1 ） The hydrothorax-peritoneum preparation were 1682 cases, the bacteria culture positive were 276 eases ,positive rate was 16.4% ,327 strains pathogenic bacteria were found in which P. aesuginosa ,S. aurus ,S. epidermidis, E. coli were seen most commonly. （ 2 ） The composition of G ＋ coccus and G - bacillus were almost equivalent in hydrothorax. G - baeillus＇s percentage was high（63.5% ） in hydroperitoneum. （3）Four pathogenic bacteria showed drug-fast to Strcptomyein, Gentamyein, Ampieillin, Carbenieillin, Clindamyein, but sensitive to Imipenem, Sulperazon, Mezlaeillin. The others were drug fast against clinical isolates at different degree. Condusions The bacteriological examination of hydrothorax-peritoneum must be done. Selecting bacteria-sensitive drug has a important value to diagnosing and treating infection of thoracic and abdominal cavity.