超声心动图评价PCI术后ACS患者左心室损害的恢复程度

The study on recovery extent of left ventricular damage in ACS after PCI by echocardiography

目的应用超声心动图(ECHO)量化评价经皮冠状动脉介入(PCI)术后急性冠脉综合征(ACS)患者左心室结构和收缩功能损害的恢复程度。方法选择经冠状动脉造影(CAG)证实存在冠状动脉狭窄或闭塞并接受PCI术的ACS患者40例,比较对照组(20例)与病例组术前、病例组术后与术前ECHO以下指标的变化:室间隔(IVS)与左室后壁(LVPW)厚度,左心室舒张末期内径(LVDd)和收缩末期内径(LVDs),左室射血分值(LVEF)和左室短轴缩短率(FS),左室舒张末期容量(LVVd)和收缩末期容量(LVVs)。结果(1)病例组术前LVEF、FS明显低于对照组(P<0.001,<0.001),病例组术前LVDs、LVVs明显高于对照组(P<0.001,<0.001)。(2)病例组术后与术前ECHO指标的比较:LVEF、FS术后明显提高(P<0.001,<0.001),LVDd、LVVd术后增大(P<0.05,<0.05),LVDs术后减小(P<0.05)。结论ECHO是量化评价PCI术后ACS患者左心室损害恢复程度的有效工具。

Objective To quantitatively evaluate the recovery extent of left ventricular （structures , motion and left ventricular systolic function） damage and in acute coronary syndromes （ACS）after percutaneous coronary intervention （PCI） by echocardiography （ECHO）. Methods This study Selected 40 hospitalized patients who were diagnosed as ACS with significant coronary artery stenosis or infarction undergoing coronary artery angiography （CAG） and PCI. We compared the changes of parameters and ultrasonic features of ECHO between before and after PCI. Received 20 normal subjects whose CAG were negative as control group. Results The changes of parameters of ECHO of 40 cases between before and after PCI：LVEF,FS,LVDd,LVVd were significant higher after PCI than those before PCI（ P 〈 0.001, 〈 0.001, 〈0.05,〈 0.05） ; LVDs was significant lower after PCI than those before PCI（ P 〈 0.05） ; the detective cases of lower left ventricular systolic function after PCI were significant less than those before PCI （ P 〈 0. 001 ） ; the detective cases of left ventrieular dilation, the thickness of IVS and LVPW, incidental rate of regional wall motion abnormal（RWMA） and others were no significant differences before and after PCI.Conclusion ECHO is the effective tool to quantitatively evaluate the recovery extent of left ventricular damage in ACS after PCI.