吉兰-巴雷综合征患者神经肌电图分析

Analysis of Electromyographical Study in Patient With Guillian-Barre Syndrome

目的:探讨吉兰—巴雷综合征(GBS)患者的神经电生理改变特点。方法:对22例GBS患者进行肌电图(EMG)、运动神经传导速度(MCV)、F波及感觉神经传导速度(SCV)检测,共检测78条运动神经,52条感觉神经,47条F波及62块肌肉,并对结果进行分析。结果:上、下肢MCV减慢占44.8%.远端潜伏期延长占24.3%,SCV减慢占38.1%,F波异常占89.3%,EMG提示神经原性改变占64.5%。结论:GBS为广泛的周围神经损害的电生理特征,F波的异常发生率明显高于MCV异常发生率,F波与MCV同时检测在吉兰—巴雷综合征诊断中有着重要的互补作用。

Objective：To investigate the electroneuographical characteristics in patients with Guillian- Barre Syndrome （GBS）. Method： EMG, MCV, F wave, and SCV were determined in 22 patients with GBS diagnosed clinically. A total of 78 motor nerves, 52 sensory nerves, 47 F waves and 62 muscles were measured, and the results were analyzed. Results： In the 78 motor nerves examined, reduction of MCV was found in 44.8% of upper and lower limbs, prolongation of the distal latency in 24.3 %, reduction of SCV in 38.1%, F waves abnormality in 89.3 %, and the neurogenic changes revealed by EMG were found in 64.5 %. Conclusion： GBS might result in widespread peripheral nerve damages. The occurrence rate of abnormal F waves was obviously higher than that of MCV, and examining both F waves and MCV simultaneously might be much helpful for each other in diagnosing GBS.