摘要
随着心血管疾病在女性中发病率的逐年升高,女性心血管疾病的药物治疗引起了广泛关注.由于女性心血管疾病的临床特点和病理生理机制具有一定特异性,药物代谢动力学也不同于男性,更好地理解这种性别差异,对临床上选择用药和药物剂量有重要指导意义.本文结合近年来临床试验的结果,对心血管疾病常用药物在女性患者中的治疗作用和不良反应以及造成性别差异的原因等方面进行论述.
With the morbidity of cardiovascular disease in women increasing, cardiovascular drug therapy in women has attracted wide concern. Since there are relative differences of the pathophysiology and clinical manifestations of cardiovascular diseases and also drug metabolsms between men and women, to better understand these differences is instructive to choose suitable drugs and decide proper dosages in women. This article is based on the evidences from recent clinical trials to discuss the specific therapeutic effects and side effects of eardiovaseular drugs in women and the reasons of such differences between the two genders.
出处
《中国心血管杂志》
2007年第2期132-134,共3页
Chinese Journal of Cardiovascular Medicine
关键词
女性
心血管疾病
药物治疗
Women
Cardiovascular disease
Medicine
