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变应性支气管肺曲菌病1例并文献复习 被引量:7

A Case With Allergic Bronchopulmonary Aspergillosis and With Literature View
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摘要 目的:提高对变应性支气管肺曲菌病(ABPA)的认识并引起对该病的重视。方法:对1例ABPA患者临床资料进行分析,并结合文献进行复习。结果:ABPA是一种慢性、免疫介导的,对寄生繁殖的曲菌过敏导致的非感染性、炎症性肺部疾病,常发生在支气管哮喘的患者。结论:目前对该病的诊断应采取多种手段,包括纤支镜检查,痰培养及影像学、免疫学等;长期吸入糖皮质激素与口服伊曲康唑能达到较好治疗效果,且最大限度减少副作用。 Objective: To enhance the awareness of allergic bronchopulmonary aspergillosis (ABPA) and pay more attention to it. Methods:The clinical data of one case with ABPA in our hospital was reported and analyzed. Results:ABPA was a chronic, immune-mediated lung disease, ususally occurrs in patients with bronchoasthma. Conclusions : ABPS should be diagnosed through various measures including bronchofibroscope, sputum culture, imaging, and immunological examinations. Long-term corticosteroid inhalation and Itraconazole oral administration may achieve a better effect, and decrease side effects.
出处 《内科急危重症杂志》 2007年第2期88-89,共2页 Journal of Critical Care In Internal Medicine
关键词 变应性支气管肺曲菌病 糖皮质激素 伊曲康唑 Allergic bronchopulmonary aspergillosis Corticosteroids Itraconazole
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参考文献7

  • 1Rosenberg M,Patterson R,Mintzer R,et al.Clinical and immunologic criteria for the diagnosis of allergic bronchopulmonary aspergillosis.Ann Intern Med,1977,86:405.
  • 2张斌,徐凯峰,林耀广.变态反应性支气管肺曲菌病[J].中华结核和呼吸杂志,1999,22(6):377-378. 被引量:17
  • 3Hartman TE,Primack SL,Lee KS,et al.CT of bronchial and bronchiolar diseases.Radiographics,1994,14:991.
  • 4Hoehne JH,Reed CE,Dickie HA.Allergic bronchopulmonary aspergillosis is not rare.With a note on preparation of antigen for immunologic tests.Chest,1973,63:177.
  • 5Nepomuceno IB,Esirg S,Moss RB.Allergic bronchopulmonary aspergillosis in cystic fibrosis:role of atopy and response to itraconazole.Chest,1999,115:364.
  • 6Wark PA,Hensley MJ,Saltos N,et al.Anti-inflammatory effect of itraconazole in stable allergic bronchopulmonary aspergillosis:a randomized controlled trial.J Allergy Clin Immunol,2003,111:952.
  • 7Balter MS,Rebuck AS.Treatment of allergic bronchopulmonary aspergillosis with inhaled corticosteroids.Respir Med,1992,86:441.

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