摘要
Objective： To explore the effect of electro-acupuncture and musk injection on recovery of injured sciatic nerve function in rats, so as to provide the experimental evidences for the promotion of peripheral nerve regeneration by electro-acupuncture and musk injection. Methods： Following establishing rat model of sciatic nerve injury by operation, the rats were randomly divided into electro-acupuncture group, musk injection group, electro-acupuncture plus musk injection group and model group, then sciatic functional index （SFI） and motor nerve conduction velocity （MNCV） were measured after 4 weeks of treatment, 8 weeks of treatment and 12 weeks of treatment respectively to evaluate recovery of nerve function. Results： SFI and MNCV in electro-acupuncture group, musk injection group and electro-acupuncture plus musk injection group were improved more obviously than that in model group, with significant differences（P〈0.01, P〈0.05）. Conclusions： Both electro-acupuncture and musk injection could promote recovery of injured nerve function, and they had a certain synergetic effect and might be the effective methods in promoting recovery of injured peripheral nerve function.
目的：探讨电针、麝香注射液对大鼠损伤坐骨神经功能恢复的作用，为临床提供电针、麝香注射液促进周围神经再生的实验依据。方法：采用手术造成清洁级SD大鼠坐骨神经损伤模型后，随机分为电针组、麝香注射液组、电针加麝香注射液组、和模型组，分别在治疗4、8、12周观察坐骨神经功能指数（sciatic functional index，SFI）和运动神经传导速度（Motor nerve conduction velocity,MNCV），判断神经功能恢复情况。结果：电针组、麝香注射液组以及电针加麝香注射液组SFI和MNCV的恢复优于模型组，差异有显著性意义（P〈0．01、P〈0．05），其中电针加麝香注射液组优于电针组或麝香注射液组，差异有显著性意义（P〈0．01）。结论：电针、麝香注射液均能促进损伤神经的功能恢复。它们有一定的协同作用，是一种促进周围神经损伤后神经功能恢复的有效手段。
