鱼腥草止咳口服液治疗难治性肺炎的临床观察

Clinical observation on Herba Houttuyniae Oral Liquid in treating hard-cured pneumonia

目的:观察鱼腥草止咳口服液对难治性肺炎患者的临床疗效,并探讨其作用机理。方法:65例患者随机分成两组,治疗组35例,对照组30例。对照组采用西医常规治疗,治疗组在同对照组治疗基础上加用鱼腥草止咳口服液口服,观察两组患者症状及体征的改善情况,并检测治疗前后外周血IL-2和TNF-α的变化。结果:治疗后总有效率:治疗组为94.3%,对照组为83.3%,组间比较有显著性差异(P<0.05);治疗组在增加外周血IL-2及降低TNF-α水平方面明显优于对照组。结论:鱼腥草止咳口服液治疗难治性肺炎具有显著疗效,尤其在镇咳、平喘、抗炎、退热及促进排痰、肺部啰音和炎症消失、毒副作用等方面具有明显优势。

Objective：To observe the clinical effect of Herba Houttuyniae Oral Liquid in treating hard-cured pneumonia and to explore its possible mechanism.Methods：sixty-five patients were randomly divided into two groups.The control group was treated with conventioral western therapy （CWT）,while the treatment group was treated with CWT plus Herba Houttuyniac Oral Liquid.The changes of serum cytokincs [L-2 and TNF-α,bcforc and after treatment were observed.Results：the total effective rate of treatment group was 94.3%,while that of the control group was 83.3%.The difference of the total effective rate between the two groups was significant（P〈0.05）.After being treated,in raising peripheral blood IL-2 level and declining TNF-α level, the treatment group was obviously superior to the control group.Conclusion：In treating intractable pneumonia, Herba Houttuyiae Oral Liquid has better curative effect and obvious merit in preventing cough, relieving gasping,anti-inflammatory pyretolysis, falling away sputamentum and few side-effect.