4Fukuda K,Hibiya Y,Mutoh M,etal.Inhibition by berberine of cyclooxygenase-2 transcriptional activity in human colon cancer cells[J].Ethnophammocl,1999,66 (2):227～ 233.
6Barreto MC.Pinto RE.Arrabaca JD et al.Inhibiton of mouse liver respirton by Chelidonium majus isoquinoline alkalids[J].Toxicol Lett,2003,146(1):37～47.
7Lin JG,Chung JG,Wu LT,et al.Effects of berberine on aryl-amine N-acetyltransferase activity in human colon tumor cells[J].Am J Chin Med,1999,27(2):265～275.
9Anis KV,Rajeshkumar NV,Kuttan R.Inhibition of chemical carcinogenesis by berberine.In rats and mice[J].J Pharm Pharmacol 2001,53(5):763～ 768.
10Lin HL,Liu TY,Lui WY,et al.Up-regulation of multidrug resistance transporter expression by berberine in human and routine hepatoma cells[J].Cancer,1999,85(9):1937～1942.
8Bresalier RS, Kim YS. Malignant neoplasms of the large intestine. In: Sleisenger MH, Fordtran JS, eds, Gastrointestinal disease: pathophysiology, diagnosis, management, Vol 2, 5th ed, Philadephia, Saunders, 1993:1449.
9Fukuda K, Hibiya Y, Mutoh M. Inhibition by berberine of cyclooxygenas-2 transcriptional activity in human colon cancer cells. J Ethnopharmacol, 1999, 66 (2): 227.
10Kuo CL, Chou CC, Yung BY. Berberine complex with DNA in the berberine-induced apoptosis in human leukemia HL-60 cells. Cancer Lett, 1995, 93 (2): 193.
9Anis KV, Rajeshkumar NV, Kuttan R. Inhibition of chemical carcinogenesis by berberine in rats and mice[J]. J Pharm Pharmacol, 2001, 53(5):763-768.
10Li XK, Motwani M, Tong W,et al. Huanglian, A chinese herbal extract, inhibits cell growth by suppressing the expression of cyclin B1 and inhibiting CDC2 kinase activity in human cancer cells [ J ] . Mol Pharmacol, 2000, 58(6):1287-1293.
