期刊文献+

阻塞性睡眠呼吸暂停低通气综合征与内皮功能

下载PDF
导出
摘要 阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypoventilation syndrome,OSAHS)是临床常见的综合征之一。该病患者睡眠时频繁发作呼吸暂停,反复出现低氧血症及高碳酸血症,导致多器官、多系统损害,尤其是心脑血管疾病。现就OSAHS与心脑血管疾病关系的研究现状进行综述,并探讨OSAHS引起血管内皮损伤的可能机制及处理对策。
出处 《中国医师进修杂志(内科版)》 2007年第5期68-69,78,共3页 Chinese Journal of Postgraduates of Medicine
  • 相关文献

参考文献3

二级参考文献19

  • 1Fletcher EC, Lesske J, Qian W, et al. Repetitive, episodic hypoxia causes diurnal elevation of blood pressure in rats. Hypertension,1992,19(6 Pt 1) :555-561.
  • 2Kang PM, Haunstetter A ,Aoki H, et al. Morphological and molecular characterization of adult cardiomyocyte apoptosis during hypoxia and reoxygenation. Circ Res,2000,87 :118-125.
  • 3Gozal D, Lipton AJ, Jones KL. Circulating vascular endothelial growth factor levels in patients with obstructive sleep apnea. Sleep,2002,25:59-65.
  • 4Thackaberry EA, Gabaldon DM, Walker MK, et al. Aryl hydrocarbon receptor null mice develop cardiac hypertrophy and increased hypoxia-inducible factor-lalpha in the absence of cardiac hypoxia.Cardiovasc Toxico1,2002 ,2 :263-274.
  • 5Lemstrom KB, Krebs R, Nykanen AI, et al. Vascular endothelial growth factor enhances cardiac allograft arteriosclerosis. Circulation,2002,105:2524-2530.
  • 6Kanagy NL,Walker BR,Nelin LD. Role of endothelin in intermittent hypoxia-induced hypertension. Hypertension, 2001,37 ( 2 Part 2 ) :511-515.
  • 7Lavie L, Hefetz A, Luboshitzky R, et al. Plasma levels of nitric oxide and L-arginine in sleep apnea patients: effects of nCPAP treatment.J Mol Neurosci,2003,21:57-63.
  • 8Shamsuzzaman AS,Winnicki M,Lanfranchi P,et al. Elevated C-reactive protein in patients with obstructive sleep apnea. Circulation,2002,105:2462-2464.
  • 9Visser M,Bouter LM,McQuillan GM,et al. Elevated C-reactive protein levels in overweight and obese adults. JAMA,1999,282:2131-2135.
  • 10Cheng TO. Gould elevated C-reactive protein in patients with obstructive sleep apnea be due to obesity per se?Circulation,2003,107:e9.

共引文献38

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部