雌激素与绝经后骨质疏松症关系的研究进展

Advances in the Relationship Between Estrogen and PMOP

绝经后骨质疏松症是一种代谢性骨疾病,是绝经后妇女雌激素水平降低导致破骨细胞的骨吸收大于成骨细胞的骨形成作用.本文对雌激素通过雌激素受体参与骨吸收和骨形成过程及其相互关联做了较为全面的阐述,揭示了雌激素降低可能是骨质疏松症的主要原因之一.

Postmenopausal osteoporosis is a kind of metabolic osteopathy, whose cause is that bone absorption of osteoclast is more forceful than osteogenesis of osteoblast. This papers reviews in detail that how estrogen and its receptor affect resorption and formation of bone, and their interactions, and reveals that estrogen diminution may be one of the main reasons for PMOP.