68株临床分离肠球菌的耐药性检测及临床意义

Detection and Clinical Meaning of Drug Resistance of 68 Strains of Clinically Isolated Enterococci

目的:了解肠球菌在临床标本中的分布及对常用的抗菌药物的耐药现状,指导临床合理用药.方法:对临床标本中分离出的细菌进行系统检验,采用纸片法对分离鉴定后的肠球菌进行药物敏感性试验.结果:肠球菌可在临床常见的多种标本中检出,粪肠球菌(86.7%)明显多于屎肠球菌(10.3%),其他肠球菌(3%)少见.对常用抗菌药物的耐药性,粪肠球菌和屎肠球菌之间的差异无统计学意义.结论:临床医生应关注临床常见病原菌的耐药性研究,参考抗菌药物敏感性试验结果调整用药种类.

Objective：To study the enterococcal distribution in clinical samples and their drug resis- tance to commonly used antibiotic and provide the guidance for rational administration. Methods： Adopting paper diffusion method to observe the drug resistance of enterococci isolated from clinical samples in our hospital and analyzing their distribution in the samples. Results： Enterococcus fae- calis accounts for 86.7 % in 68 strains of enterococci and enterococcus excrement accounts for 10. 3 %, and other kinds of enterococci were rare. There was no statistical difference between drug resistance of enterococcus excrement and that of enterococcus faecalis. Conclusion：Doctor should pay attention to the drug resistance about clinically common pathogenic bacterium and choose suitable antibiotic based on its drug resistance.