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促红素对荷瘤小鼠血栓形成影响的实验研究 被引量:1

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摘要 贫血是恶性肿瘤患者最常见的并发症之一,在接受放化疗的患者中,其发生率超过90%。基因重组人促红细胞生成素(recombinant human erythropoietin,r-HuEPO)近年来被成功地应用于改善癌症患者的贫血,然而其应用的安全性,特别是血栓形成的危险性如何值得关注和进一步研究。本研究通过荷瘤小鼠化疗相关性贫血模型的建立,评价r-HuEPO在治疗癌性贫血小鼠时是否增加血栓形成的危险性,为r-HuEPO的临床应用提供实验依据。
出处 《国际肿瘤学杂志》 CAS 2007年第4期318-319,共2页 Journal of International Oncology
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同被引文献5

  • 1Ariganello 0,Mancu so A, Di Molfetta M, et al. A new induction schedule of epoetin al fa 40000 IU in anemic patient s withadvanced lung cancer. Lung Cancer,2004,46(1):119-124.
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  • 4Patton J,Kuzur M , Liqqett W, et al. Epoet in alf a 60000IU onceweek ly foil owed by 120000IU every 3w eeks increas esand maintains hemoglobin levels in an emic cancer patients undergoingchemotherapy. On cologist, 2004,9(1):90-96.
  • 5成之福,安保国,苏州,孙衍伟,秦静.促红素低剂量与常规剂量法治疗恶性肿瘤贫血的疗效比较[J].中国医院药学杂志,2009,29(23):2023-2025. 被引量:4

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