2004～2006年廊坊市部分市直医保人群HBV标志物流行状况调查

Investigation on Epidemical Status of HBV Infection Marker in Part of Medical Insurance Group of Langfang City from 2004 to 2006

[目的]了解HBV标志物在廊坊市市直医保人群中的分布状况，为乙型肝炎的防治提供依据。[方法]2004～2006年对廊坊市市直医保部分参保人员13576人采用ELISA法进行了HBsAg、抗-HBs、HBeAg、抗-HBe和抗-HBc的测定。[结果]共调查13576人，HBsAg、抗-HBs和抗-HBc阳性率分别为2．77％、23．02％和16．60％，HBV感染率为32．34％。不同性别HBsAg、抗-HBs和抗-HBc阳性率的差异均有统计学意义（P〈0．01）；不同年龄人群HBsAg阳性率的差异有统计学意义（P〈0．01），不同职业人群差异无统计学意义（P〉0．05）。在HBsAg阳性者中，小三阳是主要的血清学类型。[结论]HBV在调查人群中为中度流行，国有企业的男性职工是HBV防治的重点。

[Objective]To investigate the distribution of HBV infection marker for prevention and treatment of hepatitis B in part of medical insurance group of Langfang city. [Methods] HBsAg, Anti-HBsAg, HBeAg, anti-HBeAg, anti-HBcAg serological marker has been screened by ELISA in part of medical insurance group of Langfang city from 2004 to 2006. [Results]The result showed that the positive rate of HBsAg, anti-HBsAg, anti-HBcAg was 2.77%, 23.02%, 16.60 % respectively and prevalence rate of HBV was 32.34 % in 13 576 people. Distinction of sex is an important factor to influence positive rate of HBsAg in this group. On the contrary, age and career had little influence to positive rate of HBsAg. HBsAg, anti-HBeAg, anti-HBcAg positive were the most important serum type in HBsAg positive group. [Conclusion]HBV showed medial prevalence in this group. Male worker in state-owned factories are the main group of HBV prevention.