HPLC法测定苯巴比妥东莨菪碱片含量的测量不确定度评价

Evaluation of Measurement Uncertainty of HPLC Method for Determination of Phenobaribital and Scopolamine Hydrobromide Tablets

评价了HPLC法测定苯巴比妥东莨菪碱片含量的测量不确定度。通过不确定度来源分析,建立不确定度的数学模型,并考察测定中的各影响因素。氢溴酸东莨菪碱、苯巴比妥的扩展不确定度分别为2.1%、1.5%,含量测定结果可表示为(108.6±2.1)%、(108.3±1.5)%。

The measurement uncertainty of the HPLC method for determination of phenobaribital and scopolamine hydrobromide tablets was evaluated. The method of evaluation was achieved by analysis of the uncertainty sources arising from the procedure of analysis. The expanded uncertainty of scopolamine hydrobromide and phenobarbital were 2.1% and 1.5 %, respectively. The contents of scopolamine hydrobromide and phenobarbital were （108.6±2.1） % and （108.3±1.5） %.