地中海贫血和G6PD缺乏联合检测在婚前检查中的价值

The value of the combined tests of thalassemia and G6PD deficiency in detection of before marriage

目的探讨地中海贫血和G6PD缺乏联合检测在婚前检查中的发病率,并指导优生优育。方法应用地中海贫血一管筛查法和G6PD比值法检测4268对婚前男女的地中海贫血和G6PD缺乏。结果4268例男性受检者中,地中海贫血者为239例,G6PD缺乏者为154例,检出率分别为5.6%和3.6%;4268例女性受检者中,地中海贫血者为248例,G6PD缺乏者为136例,检出率分别为5.8%和3.2%。结论地中海贫血和G6PD缺乏在婚前检查中有较高的发病率,在婚前进行地中海贫血和G6PD缺乏的筛查,并进行优生优育的科学指导,是避免新生儿溶血的有效途径。

Objective： To study the rate of the combined tests of thalassemia and G6PD deficiency in detection of before marriage, to direct aristogenesis and good brood. Methods： Using man - vessel screen method of thalassemia and relative value of G6PD detect thalassemia and G6PD deficiency for man and woman of detection of before marriage in 4268 duplet. Results ： In 4268 man case, thalassemia is 239 cases and G6PD deficiency is 154 cases, detection rate discern is 5. 6% and 3. 6%, In 4268 woman case, thalassemia is 248 cases and G6PD deficiency is 136 cases, detection rate discern is 5. 8% and 3. 2%. Conclusion： There are higer attack rate of thalassemia and G6PD deficiency in detection of before marriage. To screen thalassemia and G6PD deficiency in detection of before marriage and to scientific direction for aristogenesis and good brood, it is efficient channel that avoids haematolysis of newborn infant.