可注射性生物降解材料PPF修复骨缺损的研究进展

Research progress on injectable PPF biomaterial for repairing bone defect

创伤、感染、肿瘤、骨坏死及先天畸形等多种疾病引起的骨缺损临床常见，使得用于骨缺损修复的可注射性生物材料越来越被重视。已开发出骨水泥、天然衍生物及合成聚合物等多种可注射性材料。对可注射性生物降解材料聚富马酸羟基丙酯（poly（propylene fumarate），PPF）在骨缺损修复方面的研究进展做一综述。

Various diseases, such as traumatic injuries, infection, tumor, osteonecrosis, congenital abnormalities, are often associated with clinical bone defect. Therefore, injectable biomaterials for osteogenesis have gained more and more attention. At present, many injectable biomaterials including bone cements, natural derived materials and synthetic polymers have been developed. This review discusses research progress on poly （propylene fumarate） as injectable biomaterial for repairing bone defects.