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原位肝移植术后早期应用乌司他丁对肝肾功能的影响 被引量:3

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摘要 将86例行同种异体原位肝移植(OLT)患者分为对照组和乌司他丁(UTI)治疗组,比较两组术后第7天肝肾功能指标、早期并发症、肠道功能恢复时间等。结果显示,与对照组比较,治疗组术后第7天谷丙转氨酶、总胆红素、直接胆红素、肌酐明显下降,前白蛋白、转铁蛋白明显升高(P<0.05),早期并发症减少,肠道功能恢复时间快(P<0.05)。提示UTI对OLT术后早期患者的肝、肾、肠道功能有保护作用,可减少术后并发症,降低病死率。
机构地区 解放军第
出处 《山东医药》 CAS 北大核心 2007年第10期66-67,共2页 Shandong Medical Journal
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  • 1王刚,陈婷婷,高长青.乌司他丁对创伤失血性休克兔肺损伤的保护作用[J].中国危重病急救医学,2005,17(1):36-38. 被引量:25
  • 2蒋龙元,杨炼红,钟娃,何志捷,常建星,余涛,王彤,黄子通.乌司他丁对失血性休克大鼠的保护作用及其机制的研究[J].中国病理生理杂志,2005,21(9):1701-1704. 被引量:12
  • 3Naka T,Wan L,Bellomo R,et al.Kidney failure associated with liver transplantation or liver failure:the impact of continuous veno-venous hemofiltration[J].Int J Artif Organs,2004,27(11):949-955.
  • 4Matsumi M,Mizobuchi S,Kaku R,et al.Changes of urinary tripsin inhibitor in blood and urine,as well as serum cytokines in living related liver transplantation[J].Masui,2003,52(3):251-256.
  • 5Ueki M,Yokono S,Taie S,et al.Effects of ulinastatin on postoperative renal function in hepatectomized patients with liver cirrhosis[J].Masui,1997,46(2):251-255.
  • 6Shirasawa Y,Nomura T,Yoshida A,et al.Liver transplantation-associated hypercalcemia followed by acute renal dysfunction[J].Intern Med,2004,43(9):802-806.
  • 7Ueki M,Yokono S,Taie S,et al.Supplement of ulinastatin on renal function after cardiopulmonary bypass[J].Masui,2000,49(2):163-167.
  • 8Chaudry I H. Rat and mouse models of hemorrhagic-traumatic shock [M]//Schlag G, Redl H (Ed). Pathophysiology of shock,sepsis and organ failure. Berlin :Springer-Verlag, 1993 : 371.
  • 9Coopersmith C M, O'Donnell D, Gordon J I. Bel - 2 inhibits isehemia-reperfusion-indueed apoptosis in the intestinal epithelium of transgenie mice[J]. Am J Physiol, 1999,276 :G677 -686.
  • 10Oltvai Z N,Milliman C L,Korsmeyer S J. Bcl -2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death[J]. Cell, 1993,74 : 609 - 619.

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  • 1陈聪聪,周燕,柳子明,孙菊妹,王慧华,邬伟东.乌司他丁对肾缺血再灌注大鼠肾组织超微结构的影响[J].中华外科杂志,2004,42(14):877-880. 被引量:15
  • 2张海燕,陈统清,孔耀中,黄英伟.赛尼哌两剂疗法预防移植肾急性排斥反应的临床研究[J].中国临床保健杂志,2004,7(5):351-353. 被引量:4
  • 3Nakanishik,Takedas,Sakamotoa,et al.Effects of ulinastatin treatment on the cardiopulmonary by pass induced hemodynamic instability and pulmonary dysfunction[J].Crit Care Med,2006,34 (5):1351-1357.
  • 4Masudat,Satok,Nodac,et al.Protective effect of urinary trypsin inhibitor on myocardial mitochondria during hemorrhagic shock and reperfusion[J].Crit Care Med,2003,31(7):1987-1992.
  • 5Molor-Erdene P, Okajima K, Isobe H,et al. Inhibition of lipopolysac-charide-induced tissue factor expression in monocytes by urinau trypsininhibitor in vitro and invivo[ J ]. Thromb Haemost, 2005,94 ( 1 ) :136-145.
  • 6Ito K, Mizutani A, Shinitiro K, et al. Effect of ulinastatin, a human urinary trypsin inhibitor, on the oleic acid-induced acute hmg injury in rats via the inhibition of activated leukocytes[ J ]. Injury, 2005,36 (3) :387-394.
  • 7Inoue K, Takano H, Toshikazu Yoshikawa. Protective role of urinary trypsin inhibitor in acute lung injury induced by lysaccharide. Exp Biol Med ,2005,230(4) :281-287.
  • 8Sato A ,Kuwabara Y ,Shinoda N ,et al. Use of low dose dopamine, gabexate mesilate and ulinastatin reduces the water balance and pulmonary complication in thoracic esophagectomy patients [ J ]. Disesophagus,2005,18(3) :151-154.
  • 9周晨亮,夏中元.乌司他丁对大鼠控制性低血压急性肾功能损伤的保护作用[J].中国误诊学杂志,2008,8(10):2314-2315. 被引量:1
  • 10林世清,肖亮灿,黄文起.乌司他丁在手术中对机体的保护作用[J].国外医学(麻醉学与复苏分册),2001,22(6):334-335. 被引量:6

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