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人乳头状瘤病毒持续感染与宫颈癌变相关的危险因素 被引量:4

Risk Factors in Cervical Carcinogenesis and Persistent Infection with Human Papillomavirus
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摘要 宫颈癌是最常见的女性生殖道恶性肿瘤,高危型人乳头状瘤病毒(HPV)持续感染与宫颈上皮内瘤样病变及宫颈癌的发生密切相关。研究发现高危型HPV是否产生持续感染不仅与HPV基因变异及其性状改变有关,宿主自身免疫反应、遗传因素的变化对其亦具有决定性影响。上述HPV持续感染危险因素的研究正方兴未艾,有望在宫颈癌相关诊断、预后标志物方面实现突破。全文对近年来该领域的相关进展做一综述。
作者 王薇 马丁
出处 《中国肿瘤》 CAS 2007年第5期316-319,共4页 China Cancer
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