期刊文献+

胸腺肽α1的特征与功能综述 被引量:20

Review on the characteristics and function of thymosin alpha 1
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摘要 胸腺肽α1是1种广泛存在于各种生物细胞中的具有与免疫调节有关的活性多肽。此文综述了胸腺肽α1的分布、结构、生物学功能以及作用机制的研究概况。
机构地区 山东大学药学院
出处 《中国生化药物杂志》 CAS CSCD 2007年第2期136-139,共4页 Chinese Journal of Biochemical Pharmaceutics
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参考文献26

  • 1Chang Yichen,Li Min,Yang Hni,et al.Roles of thymosins in cancers and other organ systems[J].World J Surg,2005,29(3):264-270.
  • 2Spangelo B L,Pompilius M,Farrimond D D,et al.Presence ofa peptide component of thymosin fraction-5 manifesting discrete cytostatic properties in HL-60 human promyelocytic leukemia cells[J].Int Immunopharm,2005,5(7-8):1317-1329.
  • 3John W,Hadden,M D.Aspects of the immunopharmacology of thymosin[J].Clin Appl Immunology Rev,2001,(1):187-191.
  • 4Sarandeses C S,Covelo G,Diaz-Jullien,et al.Prothymosin alpha is processed to thymosin alpha 1 and thymosin alpha 11 by a lysosomal asparaginyl endopeptidase[J].J Biol Chem,2003,278 (15):13286-13293.
  • 5Grottesi A,Sette M,Palamara T,et al.The conformation of peptide T α 1 in solution and in a membrane-like environment by circular dichroism and NMR spectroscopy.A possible model for its interaction with the lymphocyte membrane[J].Peptides,1998,19(10):1731-1738.
  • 6Romani L,Bistoni F,Gaziano R,et al.Tα1 activates dendritic cells for anifungal Thl resistance through toll-like receptor signaling[J].Blood,2004,103 (11):4232-4239.
  • 7Naz R K,Kaplan P,Badamchian M,et al.Effects of synthetic T α l and its analogs on fertilizability of human sperm:search for a biologically active,stable epitope[J].Arch Androl,1995,5 (1):63-69.
  • 8周克夫,赵卿,章军,陈美,李鹰,徐虹,刘仁海.免疫组化方法研究胸腺素α1在小鼠肉瘤S180细胞中的表达[J].厦门大学学报(自然科学版),2005,44(6):741-744. 被引量:1
  • 9关有彦,周伟炜,邱雪杉.胸腺素在肿瘤研究方面的新进展[J].国外医学(生理病理科学与临床分册),2001,21(3):209-211. 被引量:2
  • 10Moody T W,Leyton J,Farah Z,et al.Thymosinαl is chemopreventive for lung adenoma formation in A/J mice[J].Cancer Lett,2000(155):121-127.

二级参考文献52

  • 1杨春,肖永红,管小琴,袁哲.拉米夫定治疗慢性乙型肝炎的临床观察及病理学研究[J].中华肝脏病杂志,2004,12(6):364-367. 被引量:24
  • 2黄小花,周克夫,章军,刘仁海,徐虹.抗胸腺素α1(Tα1)多克隆抗体的纯化及转基因藻中Tα1的检测[J].厦门大学学报(自然科学版),2004,43(B08):122-125. 被引量:2
  • 3Arase Y, Tsubota A, Suzuki Y, et al. A pilot study of thymosin alpha1 therapy for chronic hepatitis B patients. Intern Med, 2003, 42: 941-946.
  • 4Saruc M, Yuceyar H, Kucukmetin N, et al. Combination thymosin-alpha 1 and interferon-alpha 2b in the treatment of anti-HBe-positive hepatitis in Turkey. Hepatogastroenterology, 2002, 49: 798-802.
  • 5Mitani M,Kuwabara Y,Kawamura H,et al. Significance of plasma thymosin alphal 1 measurements in gastric cancer patients [J]. World J. Surg. , 2000,24: 455 -458.
  • 6Zhou Kefu,Zhang Jun, Chen Tianshen, et al. Preparationg and determination of polycolonal antibody to thymosinα[J]U. S. Chinese Jorunel of Microbiology and Immunolygy, 2001 (1):61 - 64.
  • 7Zhou Kefu,Zhang Jun, Chen Tianshen,et al. High efficient preparation and preminary application of polyclonal antibody to thymosinα1 [J]. Academic Europeenne de Sciences Naturelles, 2002,968- 971.
  • 8Goldstein A L. Clinical applications of thymosin alpha-1 [J]. Cancer Invest,1994,12:245-247.
  • 9Li C L,Zhang T,Saibara T,et al. Thymosin alpha1 accelerates restoration of T cell-mediated neutralizing antibody response in immunoeompromised hosts[J]. Int. Immunopharmacol, 2002 , 2: 39 - 46.
  • 10AncellC D, Phipps J, Young L. Thymosin alpha-1 [J].Am. J. Health Syst. Pharm, 2001,58 :879- 885.

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