倍他乐克联合参松养心胶囊对阵发性房颤患者P波离散度的影响

Therapeutic effects of betaloc combined with Shensongyangxin capsule on P wave dispersion in patients with paroxysmal atrial fibrillation

目的探讨倍他乐克及参松养心胶囊对阵发性房颤(PAF)患者P波离散度(Pd)的影响。方法将167例PAF患者作为房颤组,随机分为3亚组:A组(倍他乐克组)、B组(参松养心胶囊组)、C组(两药均用组)。以50例无房颤者作为对照组。比较房颤组及无房颤组以及3亚组间治疗前、后Pd水平的差异。结果房颤组Pd高于无房颤组(P<0.01),治疗前A、B、C3亚组Pd差异无显著意义(P>0.05),A、B、C3亚组治疗后Pd较治疗前均有显著降低,差异有显著意义(P<0.05或P<0.01),治疗后A、B亚组间Pd差异无显著意义(P>0.05),C亚组Pd明显低于A、B亚组(P<0.01)。结论倍他乐克、参松养心胶囊联用更有助于预防房颤的复发。

Objective To investigate the therapeutic effects of betalec combined with Shensengyangxin capsule on P wave dispersion （Pd） in patients with paroxysmal atrial fibrillation （PAF）. Methods 167 patients whth PAF were divided into 3 groups randomly, group A （ betaloc group）, group B （ Shensengyangxin capsule group） and group C（beth drugs group）,and 50 healthy subjects were chosen as control group. Results The Pd in PAF groups was significantly higher than that of control group （ P 〈 0.01 ）. There was no significant differences in Pd among three PAF groups （ P 〉 0.05 ）. The Pd in three PAF groups was obviously decreased after treatment, compared with that before treatment （ P 〈 0.05 or P 〈 0.01） .There was no significant difference in Pd after treatment between group A and group B （ P 〉 0.05） ,however, which in group C was significantly lower than that of group A and group B （ P 〈 0. 01 ）. Conclusion Betaloc combined with Shensongyangxin capsule is helpful to prevent the recurrence of PAF.