腹腔镜与开腹结肠癌根治术的临床对照研究

Clinic Research of laparoscope and Open Surgery in Colon Carcinoma Radical Resection

目的对腹腔镜和开腹行结肠癌根治术的治疗效果进行临床对照研究。方法选择2004年1月～2005年12月本中心行腹腔镜结肠癌根治术病例34例及行开腹结肠癌根治术病例29例，比较手术中及术后情况。结果腹腔镜组手术时间为（150±45）min，开腹组手术时间为（142±33）min，无显著性差异（P〉0．05）。腹腔镜组术中出血为（82．3±24．2）ml，开腹组为（148．2±40．5）ml，腹腔镜组明显少于开腹组（P〈0．01）；两组在肠段切除长度、淋巴结清扫范围方面比较，无显著性差异（P〉0．05）。两组术后肠道功能恢复时间分别为（2．6±1．1）d和（3．2±1．3）d，两组相比有显著性差异（P〈0．05）。结论腹腔镜结肠癌根治术能取得与开腹手术同样的肿瘤治疗效果，并具有手术切口小、手术创伤小、患者术后下床早、应激反应小等优点。

Objective To research the therapeutic efficacy of the laparoscope and open surgery in radical resection of colon carcinoma. Methods Choose the 34 cases of radical resection of colon carcinoma had done by laparoscope and 29 cases had done by open surgery from January 2004 to December 2005, compare the information of surgery and after-surgery. Result The time of laparoscope group was （150 ± 45）min, the time of open surgery group was （142±33）min, the difference has no significant（P〉0. 05）.The hemorrhage quantity in laparoscope surgery was （82.3 ±24.2）ml, the quantity in open surgery was （148.2±40.5）ml, the difference was significant（P〈0. 01）. The comparison of these two groups in intestine excision length, the scope of cutting the lymph node had no significant difference （P〉0.05）. The time of intestine functional recovery was （2.6± 1.1）d and （3.2± 1.3）d, the difference was significant（P〈0. 05）.Conclusion Laparoscope can get the same therapeutic efficacy comparing the open surgery, and own the advantages of little operative incision, little operation wound, quickly recovery and minor stress reaction.