调肝清心汤治疗室性早搏的临床研究

Clinical Study of the treatment of premature ventricular contraction with Tiao Gan Qing Xin Decoction

目的 通过临床观察验证疏肝理气、化痰清热、宁心安神法治疗室性早搏的有效性和作用机制。方法 将100例室性早搏患者随机分为治疗组52例，予以调肝清心汤治疗；对照组48例，予以西药心律平口服，4周为一疗程。结果 调肝清心汤组可明显改善症状，两组间有显著性差异（P〈0．05）。早搏疗效两组间无显著性差异（P〉0．05）。结论 调肝清心汤可显著改善患者的临床症状和动态心电图表现，减少室性早搏发生频数，降低室性早搏严重程度。

Objective To investigate the effect and discuss the mechanisms of the method of soothing liver and regulating Qi, dissipating phlegm and clearing heat, claming the mind and tranquillization for treating premature ventricular contraction （PVC）. Methods 100 patients were divided into two groups randomly Among them, 52 cases were set as treatment group treated with Tiao Gan Qing Xin Decoction, while others were in the control group with propafenone per os .The treatment course was four weeks. Results The symptoms were improved obviously in the treatment group than the in the control group. There was significant difference between both groups （P〈0.05）. But the therapeutic effect for PVC was no difference between two groups （P〉0.05）. Conclusions Tiao Gan Qing Xin Decoction can improve symptoms and the manifestation of DCG reduce the frequency of pulsation, and bring down the degree of PVC.