摘要
目的探讨人工肝血浆置换法治疗慢性重型肝炎的疗效、安全性及影响疗效的因素。方法77例慢性重型肝炎患者在综合治疗基础上给予血浆置换治疗266例次,观察其治疗前后症状、肝功能等情况及存活率。结果77例慢性重型肝炎患者经血浆置换治疗后,临床症状都得到一定程度的改善,肝功能明显好转。总存活率为62.3%(48/77),其中早期87.9%,中期47.8%,晚期7.7%,患者耐受性好。结论血浆置换对于慢性重型肝炎是一种安全有效的治疗方法,宜早期进行疗效好。
Objective To study the effect, the reliablity and the factors influencing the therapeutic results of artificial liver support system(Plasma Exchange)in the treatment of chronic severe hepatitis (CSH). Methods 77 patients with chronic severe hepatitis were treated 266 times by using the plasma exchange (PE)device on the basis of medical treatments, and their different symptom and liver funtion before and after treament were observed, and their survival rate was collected. Results 77 patients were relieved in clinical symptom and their liver functions were obviously improved after the treatment of plasma exchange. The general survival rate was 62.3% (48/77), among which the survival rate of CSH at its earlier stage was 87.9% and that of the more serious CSH was 47.8% ,while that of the most serious CSH was 7.7%. The patient' s tolerance was good. Conclusion Plasma exchange is an effective and safe means for thearpy of chronic severe hepatitis. The earlier the therapy is used, the better the effect is.
出处
《透析与人工器官》
2007年第1期25-27,共3页
Chinese Journal of Dialysis and Artificial Organs
关键词
人工肝支持系统
血浆置换
慢性重型肝炎
Artificial liver support system
Plasma exchange
Chronic severe hepatitis