期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

交替半身照射联合R-CHOP方案治疗弥漫性大B细胞淋巴瘤3例临床分析 被引量：2

Clinical analysis of the effects of alternate half-body irradiation combined with R-CHOP on diffuse large B cell lymphoma
下载PDF
导出
摘要 目的:观察交替半身照射联合利妥昔单抗(美罗华)治疗对弥漫性大B细胞淋巴瘤(DLBCL)的影响。方法:将3例DLBCL患者采用美罗华配合CHOP方案以及交替半身照射治疗,评价患者的近期疗效、生活质量、毒副反应。结果:治疗后患者近期疗效有上升趋势,无明显毒副反应。结论:交替半身照射联合美罗华治疗弥漫性大B细胞淋巴瘤有明显的增效、减毒及改善患者生活质量的作用。 Objective：To observe the near future curative effect and quality of life of patients with diffuse large B cell lymphoma （DLBCL） treated with alternate half-body irradiation combined with R-CHOP. Methods：The near future curative effect, quality of life and adverse reaction of three patients with DLBCL treated with alternate half-body irradiation combined with R-CHOP were evaluated. Results：The near future curative effect of patient has upgrade tendency and there was no obviously adverse reaction. Conclusion：The project of alternate half-body irradiation combined with R-CHOP to treat DLBCL has effect on apparente synergia and attenuation and could improve the patient＇s quality of life.
作者 孙鸿丽 沈云峰 毛玉文 周新 朱华淳
机构地区 南京医科大学附属无锡一院血液科
出处 《南京医科大学学报（自然科学版）》 CAS CSCD 北大核心 2007年第4期364-366,共3页 Journal of Nanjing Medical University(Natural Sciences)
关键词 交替半身照射 非霍奇金淋巴瘤 美罗华 alternate half-body irradiation non-Hodgkin lymphoma Mabthera
分类号 R733.4 [医药卫生—肿瘤]
  • 相关文献

参考文献12

  • 1Magni M,Di Nicola M,Devizzi L,et al.Successful in vivo purging of CD34-containing peripheral blood harvests in mantle cell and indolent lymphoma:evidence for a role of both chemotherapy and rituximab infusion[J].Blood,2000,96(3):864-869
  • 2Johnson P,Glennie M.The mechanisms of action of rituximab in the elimination of tumor cells[J].Semin Oncol,2003,30(supp 12):3-8
  • 3Landis S,Murrary T,Bolden S,et al.Cancer statistics[J].CA Cancer J Clin.1998 ;48(1):6-29
  • 4Vose JM,Link BK,Grossbard ML,et al.Phase Ⅱ study of rituximab in combination with chop chemotherapy in patients with previously untreated,aggressive nonHodgkin's lymphoma.[J].Clini Oncol,2001,19 (2):389-397
  • 5Harris NL,Jaffe ES,Stein H,et al.A revised EuropeanAmerican classification of lymphoid neoplasms:a proposal from the International Lymphoma Study Group[J].Blood,1994,84(5):1361-1392
  • 6Press OW,Eary JF,Gooley T,et al.A phrase Ⅰ / Ⅱ trial of iodine21312 to siturnomab (anti-CD20),etoposide,cyclophosphamide,and autologous stem cell transplantation for relapsed B2cell lymphomas[J].Blood,2000;96(5):2934-2942
  • 7Belhadj K,Delfau LarueMH,et al.Efficiency of in vivo purging with rituximab prior to autologous peripheral blood progenitor cell transplantation in B-cell nonHodgkin,s lymphoma:a single in2stitution study[J].Ann Oncol,2004,15 (3):504-510
  • 8Galimberti S,Guerrini F,Morabito F,et al.Quantitative molecular evaluation in autotransplant programs for follicular lymphoma:efficacy of in vivo purging by Rituximab[J].Bone Marrow Transplant,2003,32 (1):57-63
  • 9Voso MT,Pantel G,Weis M,et al.In vivo depletion of B cells using a combination of high dose cytosine arabinoside/mitoxantrone and rituximab for autografting in patients with non-Hodgkin's lymphoma[J].Br J Haematol,2000,109 (4):729-735
  • 10Demidem A,Lam T,Alas S,et al.Chimeric anti-CD20(IDEC-C2B8) monoclonal antibody sensitizes a B cell lymphoma cell line to cell killing by cytotoxic drugs[J].Cancer Biother Radiopharm,1997,12 (3):177-186

二级参考文献6

  • 1Gatter KC,Wanke RA. Diffuse large B-cell lymphoma. In:Jaffe ES,Harris NL,Stein H,Tumors: Pathology andet al. WHO Classification of Genetics of Tumors of Haematopoietic and Lymphoid Tissues [J]. Lyon:International Agency for Research on Cancer,2001,171-174.
  • 2Simon R,Durrleman S,Hoppe RT, et al. The Non-Hodgkin Lymphoma Pathologic Classification Project.Lone-term follow-up of 1153 patients with non-Hodgkin lymphomas[J]. Ann Intern Med, 1988,109:939-945.
  • 3Hans CP, Weisenburger DD, Greiner TC, et al.Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using atissue microarray[J]. Blood, 2004,103:275-282.
  • 4Colomo L, Lopez-Guillermo A, Perales M, et al. Clinical impact of the differentiation profile assessed by immunophenotyping in patients with diffuse large B-cell lymphoma[J]. Blood, 2003, 101:78-84.
  • 5Bastion Y, Blay JY, Divine M, et al. Elderly patients with aggressive non-Hodgkin's lymphoma: disease presentation, response to treatment, and survival-a Group d'Etude des Lymphomes de I' Aduhe study on 453 patients older than 69 years[J]. J Clin Oncol, 1997,15:2945-2953.
  • 6Pfreundschuh M, Trtimper L,- Schmits R, et al. Two-weekly or 3-weekly CHOP chemotherapy with or without etoposide for the treatment of elderly patients with aggressive lymphomas: results of the NHL-B2 trial of the DSHNHL[J]. Blood, 2004, 104:634-641.

共引文献2

同被引文献14

引证文献2

二级引证文献1

南京医科大学学报（自然科学版）
2007年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部