头颈部良性神经源性肿瘤^1H MRS的表现特点

Single-voxel 1H MR Spectroscopic Features of Benign Neurogenic Tumors in Head and Neck

目的:探讨头颈部良性神经源性肿瘤在单体素1HMRS上的表现特点。材料和方法:共收集经单体素1HMRS检查,并经手术病理证实的头颈部神经源性肿瘤14例(神经鞘瘤11例,神经纤维瘤2例,颈动脉体瘤1例)。采用点分析波谱法(PRESS:TE=144ms,14例)和激励回波法(STEAM:TE=30ms,11例)进行1HMRS空间定位,以胆碱和脂质代谢物为标准评价所有肿瘤。波谱图上,胆碱和脂质分别在3.2ppm和0.9-1.4ppm区域识别。结果:采用PRESS后,14例神经源性肿瘤中检测出胆碱代谢物者11例,检出脂质代谢物者6例。胆碱和脂质代谢物同时检出者5例,仅检出胆碱者6例,仅检出脂质者1例,胆碱和脂质均未检出者2例。采用STEAM后,11例肿瘤中检出胆碱代谢物和脂质者分别为3例和8例。结论:头颈部良性神经源性肿瘤的单体素1HMRS表现具有多样性,多数肿瘤以长TEPRESS上胆碱峰的显示为特点,长TEPRESS能较STEAM更好地检出良性神经源性肿瘤内的胆碱代谢物。

Purpose： The aim of this study was to present the features of benign neruogenic tumors in head and neck at single - voxel ^1H MR spectroscopy. Materials and Methods： Fourteen benign neurogenic tumors （11 Schwannomas, 2 neurofibromas and 1 carotid body tumor） in head and neck, confirmed histo - pathologically, were performed with single - voxel ^1H MR spectroscopy at a 1.5 Tesla scanner prior to operation. Point resolved spectroscopy （PRESS） at TE of 144 ms （14 tumors） and stimulated echo acquisition mode（STEAM） at TE of 30 ms（11 tumors） were utilized for localization techniques. We used choline （Cho, at 3.2 ppm） and lipid （Lip, at 0.9- 1.4 ppm） metabolites as criterions to evaluate all the benign neurogenic tumors. Results： On long TE PRESS, Cho and Lip signals were identified in 11 of 14 tumors and 6 of 11 tumors, respectively. There were 5 tumors with Cho and Lip signals, 6 tumors with only Cho, 1 tumor with only Lip, and 2 tumors without both two signals. On short TE STEAM sequence, Cho and Lip signals were separately presented in 3 of 11 tumors and 8 of 11 tumors. Conclusion： Most benign neurogenic tumors in head and neck were characterized by the presence of Cho signals with or without Lip signals on long TE PRESS. Long TE PRESS could be more sensitive in detecting Cho signals within the neurogenic tumors than short TE STEAM.