四例帕金森病患者急性运动不能及临床分析

Acute akinesia in 4 patients with Parkinson disease

目的了解帕金森病（PD）急性运动不能的临床表现。方法对56例PD住院患者进行观察，其中4例出现急性运动不能，对其运动不能时及症状改善后的运动功能评分并与以前评分比较。结果4例患者均突然出现运动症状迅速加重，均有感染性疾病为其诱因。急性运动不能迅速加重，导致患者在1～7d内Webster评分增加6．5～13．5分，Hoehn-Yahr分级自3级增至5级，并且持续8～36d。其中1例死亡。结论急性运动不能是PD伴发系统疾病时的一个严重并发症。

Objective To assess acute akinesia in patients with Parkinson disease（PD）. Methods Fifty-six patients with PD were examined, Four cases of them were admitted to our hospital because of acute akinesia. They were examined with Modified Webster scale during the akinesia state and compared with the score obtained before the onset and after recovery. Results Among 56 cases of PD, 4 patients developed acute akinesia. Acute akinesia developed secondary to infectious disease in all of them. Acute akinesia was severe enough to increase the Webster scale by 6, 5-13, 5, and Hoehn -Yahr stage from III to V, within 1 to 7 days and persisted for 8 to 36 days. Conclusions Acute akinesia is a severe complication secondary to systemic disease in patients with PD.