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低剂量激素治疗老年人类风湿关节炎的初步观察 被引量:6

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摘要 类风湿关节炎(RA)是一种以侵犯关节为主的慢性全身炎症性疾病,反复发作及慢性迁延性滑膜炎是类风湿关节炎致残的主要原因之一。伴随着人口老龄化的迅速进展,老年人RA的发病率相应增高。老年人免疫防御功能下降,而对自身抗原反应增强,老年人RA病变后果较重,且多并发数种慢性病变,对非甾体抗炎药及慢作用药耐受能力下降,严重影响了患者的生活质量。我们对老年RA关节病变患者采用口服低剂量糖皮质激素并联合慢作用药物治疗,与单纯慢作用药物治疗对照,并进行了1年随访,以探讨低剂量糖皮质激素治疗老年人RA关节病变的有效性及安全性。
出处 《中华老年医学杂志》 CAS CSCD 北大核心 2007年第4期280-282,共3页 Chinese Journal of Geriatrics
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