无痛药流钳刮术200例临床分析

Clinical Analysis of Painless Curettage Surgery after Drug Abortion

目的探讨丙泊酚、芬太尼用于孕10-15周药流后无痛钳刮术的安全性及适用性.方法选择380例孕10-15周孕妇,随机分为两组,实验组200例,对照组180例,均服米非司酮、米索前列醇片,待有宫缩及阴道流血后,实验组缓慢静推丙泊酚2 mg/kg,芬太尼0.05 mg,对照组不用任何镇痛药,进行钳刮术.结果两组孕妇镇痛效果比较有显著性差异（P〈0.001）.术中出血量两组比较差异无显著性（P〉0.05）.结论丙泊酚、芬太尼用于药流后钳刮术具有镇痛作用快,麻醉效果确切,苏醒迅速,副反应少,不影响宫缩等优点.

Objective To investigate the safety and applicability of propofol and fentanil during the painless curettage surgery after drug abortion on women who are 10 to 15 weeks pregnant. Methods 380 cases of 10 - 15 week pregnant women were randomly divided into two groups： 200 cases of trial group and 180 cases of control group. Both groups were given mifepristone and misoprostol tablets. After uterine contraction and v bleeding were detected, the trial group slowly underwent intravenous injection with propofol 2 mg/kg 0. 05 mg. No analgesics was used in the control group but curettage surgery was applied. Results differences of analgesic effects were observed in two groups （ P 〈 0. 001 ）. aginal and fentanil Significant There was no notable difference in the amount of bleeding between the two groups （ P 〉 0. 05 ）. Conclusions The application of propofol and fentanil during the painless curettage surgery after drug abortion has many advantages, such as effective analgesia and anesthesia, rapid analepsia, fewer side effects and so on.