期刊文献+

糖尿病性勃起功能障碍的血管因素 被引量:6

Vascular Factors in the Pathogenesis of Diabetic Erectile Dysfunction
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摘要 糖尿病性勃起功能障碍(DED)是一种由多因素引起的综合病症,其中血管内皮系统的损害起着重要作用。在糖尿病发展过程中,一些血管舒缩因子和生长因子有着显著的改变。这些改变与DED的发生存在明显的相关性。 Diabetic erectile dysfunction (DED) is a muhifactor syndrome, which involves vascular disease, neuropathy, metabolic control, nutrition, endocrine disorders, psychogenic factors, and anti-diabetes drugs. Among all these factors, vascular disease plays a very important role. In the development of diabetic vasculopathy, some vasomotion factors and growth factors undergo conspicuous changes, which may be significantly correlated with the development of diabetic erectile dysfunction.
出处 《中华男科学杂志》 CAS CSCD 2007年第3期255-259,共5页 National Journal of Andrology
关键词 糖尿病性勃起功能障碍 血管因素 血管舒缩因子 生长因子 diabetic erectile dysfunction vascular factor vasomotion factor growth factor
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参考文献24

  • 1Richardson D,Vinik A.Etiology and treatment of erectile failure in diabetes mellitus[J].Curr Diab Rep,2002,2(6):501-509.
  • 2Argiolas A,Melis MR.Central control of penile erection:role of the paraventricular nucleus of the hypothalamus[J].Prog Neurobiol,2005,76 (1):1-21.
  • 3Simopoulos DN,Gibbons SJ,Malysz J,et al.Corporeal structural and vascular micro architecture with X-ray micro computerized tomography in normal and diabetic rabbits:histopathological correlation[J].J Urol,2001,165 (5):1776-1782.
  • 4王为服,张元芳,丁强,徐一甄,凌治萍.糖尿病性阴茎勃起功能障碍大鼠模型海绵体超微结构的研究[J].中华泌尿外科杂志,1999,20(10):628-631. 被引量:24
  • 5Akingba AG,Burnett AL.Endothelial nitric oxide synthase protein expression,localization,and activity in the penis of the alloxan-induced diabetic rat[J].Mol Urol,2001,5(4):189-197.
  • 6Morano S.Pathophysiology of diabetic sexual dysfunction[J].J Endocrinol Invest,2003,26(3 Suppl):65-69.
  • 7De Young L,Yu D,Freeman D,et al.Effect of PDE5 inhibition combined with free oxygen radical scavenger therapy on erectile function in a diabetic animal model[J].Int J Impot Res,2003,15(5):347-354.
  • 8Disanto ME.Contractile mechanisms in diabetes-related erectile dysfunction[J].Curr Pharm Des,2005,11(31):3995-4010.
  • 9Hedlund P,Alm P,Andersson KE.NO synthase in cholinergic nerves and NO-induced relaxation in the rat isolated corpus cavernosum[J].Br J Pharmacol,1999,127 (2):349-360.
  • 10Bivalacqua TJ,Usta MF,Champion HC,et al.Endothelial dysfunction in erectile dysfunction:role of the endothelium in erectile physiology and disease[J].J Androl,2003,24(6 Suppl):S17-S37.

二级参考文献15

  • 1Yu-TianDAI,VivienneStopper,RonaldLewis,ThomasMills.Effects of castration and testosterone replacement on veno-occlusion during penile erection in the rat[J].Asian Journal of Andrology,1999,1(1):53-59. 被引量:4
  • 2陈修 陈维洲 等.心血管药理学[M].北京:人民卫生出版社,1997.324-325.
  • 3王为服,王忠.左旋精氨酸-一氧化氮-环磷酸鸟苷通路与阴茎勃起[J].国外医学(泌尿系统分册),1997,17(1):13-17. 被引量:7
  • 4王为服,国外医学.泌尿系统分册,1997年,17卷,13页
  • 5Wang C Y,Urol Int,1993年,50卷,209页
  • 6Jackson G. Sexual dysfunction and diabetes [ J ]. Int J Clin Pract,2004, 58(4) :358-362.
  • 7Dorrance AM, Lewis RW, Mills TM. Captopril treatment reverses erectile dysfunction in male stroke prone spontaneously hypertensive rats[J]. Int J Impot Res, 2002, 14(6) :494-497.
  • 8Johnston CI. Biochemistry and pharmacology of the renin-angiotensin system[ J]. Drugs, 1990, 39(Suppl 1 ) :21-31.
  • 9Heaton JP, Varrin SJ, Morales A. The characterization of a bioassay of erectile function in a rat model[J]. J Urol, 1991, 145(5) :1099-1102.
  • 10Parving HH. Angiotensin-converting enzyme inhib ition in diabetes: above and beyond the beneficial effect of blood pressure [ J] ?Curr Hypertens Res, 2004, 6 (5) :366-368.

共引文献31

同被引文献85

  • 1李进兵,黄道中,饶可,张青萍,赵胜,李银珍.彩色多普勒超声对血管性阴茎勃起功能障碍诊断的价值[J].中国超声医学杂志,2005,21(7):525-528. 被引量:13
  • 2中国2型糖尿病勃起功能障碍多中心调查协作组.2型糖尿病患者勃起功能障碍患病率及西地那非的疗效和安全性评价[J].中华内分泌代谢杂志,2005,21(4):348-352. 被引量:36
  • 3黄淑妍,陈澍,凤仪萍.糖尿病性勃起功能障碍研究进展[J].中华男科学杂志,2006,12(2):178-180. 被引量:12
  • 4李进兵,沈嫱,黄道中,张青萍,石小红,沈建红,覃勇.勃起功能障碍患者阴茎螺旋动脉的彩色多普勒研究[J].中国超声医学杂志,2006,22(10):777-779. 被引量:4
  • 5Malavige LS, Levy JC. Erectile Dysfunction in Diabetes Mellitus. J Sex Med, 2009.
  • 6Chen Y, Yang R, Yao L, et al. Differential expression of neurotrophins in penises of streptozotocin - induced diabetic rats. J Androl, 2007, 28(2) : 306 -312.
  • 7Pu XY, Wang XH, Gao WC, et al. Insulin - like growth factor - 1 restores erectile function in aged rats: modulation the integrity of smooth muscle and nitric oxide - cyclic guanosine monophosphate signaling activity.J Sex Med, 2008, 5(6) : 1345 -1354.
  • 8Angulo J, Cuevas P, Fernandez A, et al. Enhanced thromboxane receptor - mediated responses and impaired endothelium - dependent relaxation in human corpus cavernosum from diabetic impotent men: role of protein kinase C activity. J Pharmacol Exp Ther, 2006, 319(2) : 783 -789.
  • 9Chen Y, Li SX, Yao LS, et al. Valsartan treatment reverses erectile dysfunction in diabetic rats. Int J Impot Res, 2007, 19 (4) : 366 - 370.
  • 10Basu A, Ryder RE. New treatment options for erectile dysfunction in patients with diabetes mellitus. Drugs, 2004, 64 (23) : 2667 -2688.

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