冠心病患者餐后高血糖与心率变异性的关系探讨

The relationship between postprandial hyperglycemia andheart rate variability in patients with coronary artery disease

目的探讨冠心病患者餐后高血糖与心率变异性(HRV)的关系。方法86例冠心病患者均行糖耐量实验(OGTT)和24 h动态心电监测HRV,并根据OGTT结果分为糖耐量异常组和糖耐量正常组。结果糖耐量异常组餐后2 h血糖明显高于糖耐量正常组,差异有显著性(P<0.05);心率变异性参数糖耐量异常组低于正常组,两组比较具有显著性差异(P<0.05)。经直线相关分析发现,餐后2 h血糖水平与HRV各参数具有负相关关系。结论冠心病患者餐后高血糖与心率变异性呈负相关关系,应重视餐后血糖对心血管的影响。

Object： To discuss the relationship between postprandial hyperglycemia and heart rate variability （HRV） in patients with coronary artery disease. Methods： 86 patients with coronary artery disease were monitored by 24 - hour dynamic electrocardiogram and OGTT test. According to the results of OGTT test, the patients were divided into two groups： IGT group and non -IGT group. Result：The 2 -hour postprandial glucose （2hPG） in the IGT group was significantly higher than the comparison group, while the parameters of HRV in opposition to the result, the line correlation analysis showed that the level of postprandial hyperglycemia was negatively correlated with the parameters of HRV. Conclusion： There is a negative correlation between postprandial hyperglycemia and heart rate variability （HRV） in patients with CAD, and it is important to pay attention to the postprandial hyperglycemia in CAD patients.