多巴酚丁胺负荷超声心动图检测法乐四联症患儿左心室收缩功能

Left ventricular systolic function before total correction of tetralogy of Fallot during dobutamine stress echocardiography

为测定法乐四联症(TOF)患儿根治术前左心室的收缩功能,应用多巴酚丁胺负荷超声心动图技术(DSE)检测了25例TOF患儿及8例正常儿童的左心室短轴缩短率(FS)、射血分数(LVEF)和应变率(MVCFC)。结果:静息状态下,FS:患儿组为42.57,对照组为38.07;LVEF:患儿组为0.80,对照组为0.76;MVCFC:患儿组为1.48,对照组为1.29。经t检验,P均>0.05。DSE检测中各指标最大增高率,FS:患儿组为19%,对照组为37%;LVEF:患儿组为9%,对照组为16%;MVCFC:患儿组为22%,对照组为39%。经t检验,P均<0.01。研究提示:TOF根治术前静息状态时左心室收缩功能正常,而药物负荷下射血功能储备减低,说明TOF存在潜在的左心室收缩功能不全。

To evaluate the left ventricular systolic function before total correction of tetralogy of Fallot (TOF), 25 children before total correction of TOF and 8 normal controls were examined by dobutamine stress echocardiography (DSE). The results showed that resting left ventricular fractional shortening (FS) in TOF and controls was 42.57 and 38.07, respectively, left ventricular ejection fraction (LVEF) was 0.80 and 0.76, respectively, and strain rate (MVCFC) was 1.48 and 1.29 (P>0.05) During DSE testing, the maximal increment of FS was 19% and 37%, of LVEF was 90/00 and 16% and of MVCFC was 22% and 39% in TOF and controls, respectively (P<0.01). In conclusion, resting left ventricular ejection function was normal but cardiac reserve was poor during DSE testing before total correction of TOF.