二噁英与子宫内膜异位症发病关系的研究进展
摘要
子宫内膜异位症（endometriosis．EMs）属于良性却具有类似肿瘤侵袭、种植的特点，近年发病率明显上升，严重影响患者的生活质量。其发病机制不清，除以往的子宫内膜种植、淋巴及静脉播散、免疫、遗传等因素外．近年研究表明环境毒素二噁英（dioxin）与EMs的发生关系密切．多项资料表明二噁英不仅可导致EMs的发生，且可促进异位子宫内膜的发展，但其机制尚不清楚。现就近期关于二嗯英致EMs发生发展的机制研究做一综述。
出处
《实用医学杂志》
CAS
2007年第8期1269-1271,共3页
The Journal of Practical Medicine
参考文献18
-
1Rier S E,Turner W E,Martin D C,et al.Serum levels of TCDD and dioxin-like chemicals in Rhesus monkeys chronically exposed to dioxin:correlation of increased serum PCB levels with endometriosis[J].Toxicol Sci,2001,59(1):147-159.
-
2Mayani A,Barel S,Soback S,et al.Dioxin concentrations in women with endometriosis[J].Hum Reprod,1997,12(2):373-375.
-
3Eskenazi B,Mocarelli P,Warner M,et al.Serum dioxin concentrations and endometriosis:a cohort study in Seveso,Italy[J].Environ Health Perspect,2002,110(7):629-634.
-
4Pauwels A,Schepens PJ,D'Hooghe T,et al.The risk of endometriosis and exposure to dioxins and polychlorinated biphenyls:a case-control study of infertile women[J].Hum Reprod,2001,16(10):2050-2055.
-
5Cummings A M,Metcalf J L,Birnbaum L.Promotion of endometriosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats and mice:time-dose dependence and species comparison[J].Toxicol Appl Pharmacol,1996,138(1):131-139.
-
6Johnson K L,Cummings A M,Birnbaum L S.Promotion of endometriosis in mice by polychlorinated dibenzo-p-dioxins,dibenzofurans,and biphenyls[J].Environ Health Perspect,1997,105(7):750-755.
-
7Yang J Z,Agarwal S K,Foster W G.Subchronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin modulates the pathophysiology of endometriosis in the cynomolgus monkey[J].Toxicol Sci,2000,56(2):374-381.
-
8Heimler I,Rawlins R G,Owen H,et al.Dioxin perturbs,in a dose-and timedependent fashion,steroid secretion,and induces apoptosis of human luteinized granulosa cells[J].Endocrinology,1998,139(10):4373-4379.
-
9Bruner-Tran K L,Rier S E,Eisenberg E,et al.The potential role of environmental torins in the pathophysiology of endometriosis[J].Gynecol Obstet Invest,1999,48 (Suppl 1):45-56.
-
10Koninckx P R.The physiopathology of endometriosis:pollution and dioxin[J].Gynecol Obstet Invest,1999,47 (Suppl 1):47-49.
-
1栾宏.子宫内膜异位症病因研究进展[J].黑龙江医药科学,2004,27(3):95-96. 被引量：1
-
2方庆仙,林俊,张信美.二噁英与子宫内膜异位症相关性的研究进展[J].国外医学（妇幼保健分册）,2004,15(1):56-59. 被引量：2
-
3丁岩,温浩.基因变异与子宫内膜异位症的发生[J].国外医学（妇产科学分册）,2003,30(6):372-375. 被引量：1
-
4张萍,姜志清.126例子痫病例分析[J].泰州职业技术学院学报,2002,2(1):49-50.
-
5夏彩萍.重复异位妊娠29例临床分析[J].交通医学,2006,20(3):322-322.
-
6罗敏.卵巢功能早衰27例临床观察[J].中国现代药物应用,2012,6(7):35-36.
-
7孟文颖.药物保守治疗输卵管妊娠的疗效分析[J].中国实验方剂学杂志,2010,16(5):243-244. 被引量：3
-
8皇甫惠丽.子宫内膜异位症病因探讨[J].实用医技杂志,2005,12(10B):3013-3014.
-
9方庆仙,张信美,林俊.二噁英对子宫内膜异位症患者子宫内膜细胞TNF-α表达的影响[J].生殖与避孕,2011,31(7):449-454. 被引量：3
-
10石素兰.子宫腺肌病127例误诊分析[J].中国误诊学杂志,2010,10(28):6926-6926.
