摘要
视网膜缺血再灌注损伤是目前临床上常见的眼病,主要发生于视网膜中央动静脉栓塞、急性闭角性青光眼、糖尿病性视网膜病等视网膜血管阻塞所引起的缺血性眼病。表现为许多缺血性眼病患者在血液再通后,视网膜损伤严重,视功能反而进一步下降。视网膜缺血再灌注损伤是多因素综合作用的结果,主要包括氧自由基的损伤作用,细胞内的钙超载现象,白细胞作用以及细胞凋亡等。本文就国内外有关视网膜缺血再灌注损伤的治疗进展综述如下。
Retinal ischemia-reperfusion injury is a common oculopathy when retinal arteries become occluded in central retinal artery occlusion, acute angle-closure glaucoma or diabetic retinopathy. The resulting ischemia can cause serious retinal damage and descending visual function. Multiple factors cause retinal ischemia-reperfusion injury, including the injury effect of oxygen-derived free radicals, intracellular caldum overload, the action of leucocyte and apoptosis. The present paper reviews the progression in the treatment of retinal ischemia-reperfusion injury.
出处
《国际眼科杂志》
CAS
2007年第2期475-477,共3页
International Eye Science
