视网膜静脉阻塞患者血浆TXB_2、6-K-PGF_(1α)改变与气血辨证关系的研究

Study of the relationship between the changes in plasma B2(TXB2),F1α(6-K-PGF1a) and the differentiation of symptoms and signs qi and blood in patients with RVO

目的:探讨视网膜静脉阻塞(RVO)患者血浆血栓素B2(TXB2)、6-酮-前列腺素F1α(6-K-PGF1α)改变与气血辨证的内在关系。方法:对53例患者进行中医气血辨证与TXB2、6-K-PGF1α水平对比观察。结果:RVO患者血浆TXB2及6-K-PGF1α水平明显高于正常对照组(P<0.01),其结果与瘀血的形成机理相吻合。气虚血瘀型与气滞血瘀型相比较则无显著性差异(P>0.05)。结论:本病在中医辨证中不论病因如何,其客观结果皆是瘀血形成为致盲的首要因素。注重急症的瘀血证候,而不着重强调原发病因,这和中医的“急则治其标”的认识是相吻合的,提示治疗应以活血化瘀为主。

AIM： In order to find the inherent relationship between the changes in plasma B2（TXB2）, Fla （6-K-PGFla） and the differentiation of syndromes in qi and blood in patients with RVO. METHDS： we studied 53 cases and made observation of B2（TXB2）, F1α （6-K-PGF1a）. RESULT： The level of plasma B2（TXB2）, F1α （6-K-PGF1a）in the patients with RVO is much higher than the ordinary comparing group （P〈0.01）, these results agreed with the mechanism of the forma significant. No significant difference （P 〉0. 05） was found in the comparing between stagnancy of blood due to deficiency of qi to stagnancy of blood and qi. CONCLUSION： Regardless of the causes of the obstruction in the differentiation of symptoms and signed in Traditional Chinese Medicine, the final result was the formation of blood stasis which leaded to blindness. So it was believed that the symptoms of blood stasis ,should be emphasized, while the original mechanism of the diseases ,should be emphasized. This was identical to the traditional Chinese medicine theory of ＂When in urgency the illness is cured superficially＂, which ,showed that treatment ,should be based on promoting blood circulation and removing blood stasis.