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结直肠癌患者IL-6基因启动子-174G→C多态性研究 被引量：3

Investigation of-174G→C polymorphism of the IL-6 gene promoter in patients with colorectal cancer
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摘要 目的观察结直肠癌患者是否存在IL-6基因启动子-174G→C位点的多态性。方法采用PCR扩增、限制性内切酶片段长度多态性(RFLP)分析判断46例结直肠患者IL-6启动子-174G→C多态性。结果全组结直肠癌患者IL-6基因启动子-174位点均为GG型。结论本组结直肠癌患者中未发现IL-6基因启动子-174位点的多态性。 Objective To detect - 174G→C polymorphism of IL-6 gene promoter in patients with colorectal cancer. Methods - 174G→C polymorphism of IL-6 gene promoter was detected by PCR-RFLP in 49 patients with colorectal cancer, Results - 174G→C polymorphism of IL-6 gene promoter in all the 46 patients with colorectal cancer was - 174G/G genotype, Condusions - 174G→C polymorphism of IL-6 gene promoter was not found in 49 patients with colorectal cancer,
作者 陈江辉 李登清 陈子华
机构地区 中南大学湘雅医院麻醉科 中南大学湘雅医学院检验系
出处 《中国普通外科杂志》 CAS CSCD 2007年第4期338-340,共3页 China Journal of General Surgery
关键词 结直肠肿瘤 白细胞介素6 基因多态性 基因 结构 Colorectal Neoplasms Interleukin-6 Gene Polymorphism Gene, Structural
分类号 R735.3 [医药卫生—肿瘤]
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参考文献9

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二级引证文献18

中国普通外科杂志
2007年 第4期

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